about
Bipyrimidine Photoproducts Rather than Oxidative Lesions Are the Main Type of DNA Damage Involved in the Genotoxic Effect of Solar UVA Radiation †Resistance of bacterial endospores to outer space for planetary protection purposes--experiment PROTECT of the EXPOSE-E missionNovel thermostable Y-family polymerases: applications for the PCR amplification of damaged or ancient DNAsOne-electron oxidation reactions of purine and pyrimidine bases in cellular DNAStructural study of DNA duplex containing an N-(2-deoxy- -D-erythro-pentofuranosyl) formamide frameshift by NMR and restrained molecular dynamicsRepair and replication of oxidized DNA bases using modified oligodeoxyribonucleotidesThe COX-2 inhibitor nimesulide suppresses superoxide and 8-hydroxy-deoxyguanosine formation, and stimulates apoptosis in mucosa during early colonic inflammation in ratsSite-specific incorporation of the 1-hexanol-1,N6-etheno-2'-deoxyadenosine adduct into oligodeoxyribonucleotides.Formation of a methide derivative upon photolysis of thymidine bromohydrins.Excision of 8-methylguanine site-specifically incorporated into oligonucleotide substrates by the AlkA protein of Escherichia coli.Repair and mutagenic potential of oxaluric acid, a major product of singlet oxygen-mediated oxidation of 8-oxo-7,8-dihydroguanine.Modulation of exogenous and endogenous levels of thioredoxin in human skin fibroblasts prevents DNA damaging effect of ultraviolet A radiation.Effects of UV and visible radiations on cellular DNA.MALDI-TOF mass spectrometry as a powerful tool to study enzymatic processing of DNA lesions inserted into oligonucleotides.Minor contribution of direct ionization to DNA base damage inducedby heavy ions.Creating context for the use of DNA adduct data in cancer risk assessment: II. Overview of methods of identification and quantitation of DNA damage.Oxidatively generated base damage to cellular DNA.Unusually large deuterium discrimination during spore photoproduct formation.Measurement of oxidatively generated base damage in cellular DNA.Oxidative base damage to DNA: specificity of base excision repair enzymes.Excited singlet molecular O₂(¹Δg) is generated enzymatically from excited carbonyls in the darkCellular background level of 8-oxo-7,8-dihydro-2'-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up.Alkyltransferase-like protein (eATL) prevents mismatch repair-mediated toxicity induced by O6-alkylguanine adducts in Escherichia coli.Survival of spores of the UV-resistant Bacillus subtilis strain MW01 after exposure to low-earth orbit and simulated martian conditions: data from the space experiment ADAPT on EXPOSE-E.Riboflavin and UV-light based pathogen reduction: extent and consequence of DNA damage at the molecular level.Insight in DNA Repair of UV-induced Pyrimidine Dimers by Chromatographic Methods.Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation.Resveratrol enhances UVA-induced DNA damage in HaCaT human keratinocytes.Artifacts associated with the measurement of oxidized DNA bases.Generation of guanine-thymine cross-links in human cells by one-electron oxidation mechanismsAn organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride.Inter-strand photoproducts are produced in high yield within A-DNA exposed to UVC radiationMechanistic aspects of hydration of guanine radical cations in DNA.Oxidatively generated base damage to cellular DNA by hydroxyl radical and one-electron oxidants: similarities and differences.Oxidative damage to DNA: formation, measurement and biochemical features.Are we sure we know how to measure 8-oxo-7,8-dihydroguanine in DNA from human cells?Oxidative degradation pathways of cellular DNA: product formation and mechanistic insights.ATP-dependent chromatin remodeling is required for base excision repair in conventional but not in variant H2A.Bbd nucleosomes.Oxidation of the sugar moiety of DNA by ionizing radiation or bleomycin could induce the formation of a cluster DNA lesion.Type I and Type II Photosensitized Oxidation Reactions: Guidelines and Mechanistic Pathways.
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P50
description
hulumtuese
@sq
onderzoeker
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researcher
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հետազոտող
@hy
name
Jean Cadet
@ast
Jean Cadet
@en
Jean Cadet
@es
Jean Cadet
@nl
Jean Cadet
@sl
type
label
Jean Cadet
@ast
Jean Cadet
@en
Jean Cadet
@es
Jean Cadet
@nl
Jean Cadet
@sl
prefLabel
Jean Cadet
@ast
Jean Cadet
@en
Jean Cadet
@es
Jean Cadet
@nl
Jean Cadet
@sl
P106
P21
P31
P496
0000-0003-2594-9485