Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.
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Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligandsIslet cell autoantigen of 69 kDa is an arfaptin-related protein associated with the Golgi complex of insulinoma INS-1 cellsThe Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesionRhoG signals in parallel with Rac1 and Cdc42Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1p619, a giant protein related to the chromosome condensation regulator RCC1, stimulates guanine nucleotide exchange on ARF1 and Rab proteinsThe molecular basis of the Caskin1 and Mint1 interaction with CASKThe PHCCEx domain of Tiam1/2 is a novel protein- and membrane-binding moduleIdentification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cellsPLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migrationHuman enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiaeIdentification of a novel Rac1-interacting protein involved in membrane rufflingVE-cadherin regulates endothelial actin activating Rac and increasing membrane association of TiamActivation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas.Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascadeOligomerization of DH domain is essential for Dbl-induced transformationThe 'invisible hand': regulation of RHO GTPases by RHOGDIsmiR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cellsTumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1Paracingulin regulates the activity of Rac1 and RhoA GTPases by recruiting Tiam1 and GEF-H1 to epithelial junctionsRhoG GTPase controls a pathway that independently activates Rac1 and Cdc42HsRegulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activationIdentification of a novel, putative Rho-specific GDP/GTP exchange factor and a RhoA-binding protein: control of neuronal morphologyAnkyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migrationVav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancerRho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and diseaseMutationally activated Rho GTPases in cancerTiam1 transgenic mice display increased tumor invasive and metastatic potential of colorectal cancer after 1,2-dimethylhydrazine treatmentThe Rac GTP exchange factor TIAM-1 acts with CDC-42 and the guidance receptor UNC-40/DCC in neuronal protrusion and axon guidanceCrystal structure of human RhoA in a dominantly active form complexed with a GTP analogueRom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae.Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity.Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neuronsRalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for RalIntegrins as receptors for lamininsInteraction of GRASP, a protein encoded by a novel retinoic acid-induced gene, with members of the cytohesin family of guanine nucleotide exchange factorsGuanine nucleotide exchange factor, Tiam1, directly binds to c-Myc and interferes with c-Myc-mediated apoptosis in rat-1 fibroblastsIdentification of a novel breast-cancer-anti-estrogen-resistance (BCAR2) locus by cell-fusion-mediated gene transfer in human breast-cancer cellsRhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domainIdentification of a mouse p21Cdc42/Rac activated kinase
P2860
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P2860
Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh-hant
name
Identification of an invasion- ...... hangers for Rho-like proteins.
@en
Identification of an invasion- ...... hangers for Rho-like proteins.
@nl
type
label
Identification of an invasion- ...... hangers for Rho-like proteins.
@en
Identification of an invasion- ...... hangers for Rho-like proteins.
@nl
prefLabel
Identification of an invasion- ...... hangers for Rho-like proteins.
@en
Identification of an invasion- ...... hangers for Rho-like proteins.
@nl
P2093
P1433
P1476
Identification of an invasion- ...... hangers for Rho-like proteins.
@en
P2093
Collard JG
Scholtes EH
Zuydgeest D
van der Kammen RA
P304
P356
10.1016/0092-8674(94)90216-X
P407
P577
1994-05-01T00:00:00Z