Mutations of the E-cadherin gene in human gynecologic cancers.
about
Regulatory Variants and Disease: The E-Cadherin -160C/A SNP as an ExampleE-cadherin and APC compete for the interaction with beta-catenin and the cytoskeletonE-cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancersHypoxia attenuates the expression of E-cadherin via up-regulation of SNAIL in ovarian carcinoma cellsTumor suppressor gene E-cadherin and its role in normal and malignant cellsLow frequency of E-cadherin alterations in familial breast cancerE-cadherin and gastric cancer: cause, consequence, and applicationsFunctional loss of E-cadherin and cadherin-11 alleles on chromosome 16q22 in colonic cancerIdentification of an invasive, N-cadherin-expressing epithelial cell type in endometriosis using a new cell culture modelE-cadherin gene mutations in signet ring cell carcinoma of the stomach.DNA hypermethylation and clinicopathological features in breast cancer: the Western New York Exposures and Breast Cancer (WEB) Study.Rac1 and Rho contribute to the migratory and invasive phenotype associated with somatic E-cadherin mutation.Estrogen regulates Snail and Slug in the down-regulation of E-cadherin and induces metastatic potential of ovarian cancer cells through estrogen receptor alpha.Genetic events and the role of TGF beta in epithelial tumour progression.Regulation of E-cadherin: does hypoxia initiate the metastatic cascade?Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression.Involvement of members of the cadherin superfamily in cancerSequence-based detection of mutations in cadherin 1 to determine the prevalence of germline mutations in patients with invasive lobular carcinoma of the breast.The E-cadherin repressor slug and progression of human extrahepatic hilar cholangiocarcinoma.Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas.Cadherin and catenin alterations in human cancer.E-cadherin destabilization accounts for the pathogenicity of missense mutations in hereditary diffuse gastric cancer.Simultaneous loss of E-cadherin and catenins in invasive lobular breast cancer and lobular carcinoma in situ.The dominance of the microenvironment in breast and ovarian cancer.Sequential molecular and cellular events during neoplastic progression: a mouse syngeneic ovarian cancer model.Mechanisms of tumour invasion and metastasis: emerging targets for therapy.Identification and characterization of CDH1 germline variants in sporadic gastric cancer patients and in individuals at risk of gastric cancer.TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancerThe E-cadherin gene (CDH1) variants T340A and L599V in gastric and colorectal cancer patients in Korea.Allelic analysis of serous ovarian carcinoma reveals two putative tumor suppressor loci at 18q22-q23 distal to SMAD4, SMAD2, and DCC.Nonmalignant epithelial cells, potentially invasive in human endometriosis, lack the tumor suppressor molecule E-cadherinDiffuse type gastric and lobular breast carcinoma in a familial gastric cancer patient with an E-cadherin germline mutation.Analysis of E-cadherin in diffuse-type gastric cancer using a mutation-specific monoclonal antibody.Gypsy retrotransposon as a tool for the in vivo analysis of the regulatory region of the optomotor-blind gene in DrosophilaAbnormal expression of integrin alpha 6 beta 4 in cervical intraepithelial neoplasiaNovel mutations target distinct subgroups of medulloblastoma.The genomics and genetics of endometrial cancer.E-cadherin in gastric cancerLow frequency of germline E-cadherin mutations in familial and nonfamilial gastric cancerE-cadherin gene mutations are rare in adenocarcinomas of the oesophagus.
P2860
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P2860
Mutations of the E-cadherin gene in human gynecologic cancers.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh-hant
name
Mutations of the E-cadherin gene in human gynecologic cancers.
@en
Mutations of the E-cadherin gene in human gynecologic cancers.
@nl
type
label
Mutations of the E-cadherin gene in human gynecologic cancers.
@en
Mutations of the E-cadherin gene in human gynecologic cancers.
@nl
prefLabel
Mutations of the E-cadherin gene in human gynecologic cancers.
@en
Mutations of the E-cadherin gene in human gynecologic cancers.
@nl
P2093
P356
P1433
P1476
Mutations of the E-cadherin gene in human gynecologic cancers.
@en
P2093
P2888
P304
P356
10.1038/NG0594-98
P407
P577
1994-05-01T00:00:00Z
P6179
1005859618