Translation elongation factor eEF1A2 is essential for post-weaning survival in mice.
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The translation elongation factor eEF1A1 couples transcription to translation during heat shock responseThe eEF1A Proteins: At the Crossroads of Oncogenesis, Apoptosis, and Viral InfectionsBiallelic mutations in the gene encoding eEF1A2 cause seizures and sudden death in F0 miceStructural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation.Generation of a cholangiocyte-specific cDNA expression library for the identification of B and T cell autoantigens in murine biliary disease.Co-expression analysis of fetal weight-related genes in ovine skeletal muscle during mid and late fetal development stages.Haploinsufficiency for translation elongation factor eEF1A2 in aged mouse muscle and neurons is compatible with normal function.Characterisation of translation elongation factor eEF1B subunit expression in mammalian cells and tissues and co-localisation with eEF1A2.Impaired protein translation in Drosophila models for Charcot-Marie-Tooth neuropathy caused by mutant tRNA synthetasesRaf kinases mediate the phosphorylation of eukaryotic translation elongation factor 1A and regulate its stability in eukaryotic cells.Treatment with didemnin B, an elongation factor 1A inhibitor, improves hepatic lipotoxicity in obese miceInappropriate expression of the translation elongation factor 1A disrupts genome stability and metabolism.Heterozygous mutation of eEF1A1b resulted in spermatogenesis arrest and infertility in male tilapia, Oreochromis niloticusSer/Thr kinases and polyamines in the regulation of non-canonical functions of elongation factor 1A.eEF1A phosphorylation in the nucleus of insulin-stimulated C2C12 myoblasts: Ser⁵³ is a novel substrate for protein kinase C βI.In vivo characterization of the role of tissue-specific translation elongation factor 1A2 in protein synthesis reveals insights into muscle atrophy.Loss of translation elongation factor (eEF1A2) expression in vivo differentiates between Wallerian degeneration and dying-back neuronal pathology.Regulation of mRNA Translation in Neurons-A Matter of Life and Death.Components of the translational machinery are associated with juvenile glycine receptors and are redistributed to the cytoskeleton upon aging and synaptic activity.Structural rationale for the cross-resistance of tumor cells bearing the A399V variant of elongation factor eEF1A1 to the structurally unrelated didemnin B, ternatin, nannocystin A and ansatrienin B.Homozygous EEF1A2 mutation causes dilated cardiomyopathy, failure to thrive, global developmental delay, epilepsy and early death.The expression profile and prognostic significance of eukaryotic translation elongation factors in different cancers.
P2860
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P2860
Translation elongation factor eEF1A2 is essential for post-weaning survival in mice.
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2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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name
Translation elongation factor eEF1A2 is essential for post-weaning survival in mice.
@en
Translation elongation factor eEF1A2 is essential for post-weaning survival in mice.
@nl
type
label
Translation elongation factor eEF1A2 is essential for post-weaning survival in mice.
@en
Translation elongation factor eEF1A2 is essential for post-weaning survival in mice.
@nl
prefLabel
Translation elongation factor eEF1A2 is essential for post-weaning survival in mice.
@en
Translation elongation factor eEF1A2 is essential for post-weaning survival in mice.
@nl
P2093
P2860
P356
P1476
Translation elongation factor eEF1A2 is essential for post-weaning survival in mice.
@en
P2093
Bergmann JH
Brownstein D
Newbery HJ
O'Donoghue JE
Tomlinson VA
P2860
P304
28951-28959
P356
10.1074/JBC.M703962200
P407
P50
P577
2007-07-19T00:00:00Z