Signaling mechanisms involved in the activation of arachidonic acid metabolism in human astrocytoma cells by tumor necrosis factor-alpha: phosphorylation of cytosolic phospholipase A2 and transactivation of cyclooxygenase-2.
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Cyclooxygenase in the treatment of glioma: its complex role in signal transductionEffect of 4-trifluoromethyl derivatives of salicylate on nuclear factor kappaB-dependent transcription in human astrocytoma cellsRat brain cortex mitochondria release group II secretory phospholipase A(2) under reduced membrane potential.Rat brain docosahexaenoic acid metabolism is not altered by a 6-day intracerebral ventricular infusion of bacterial lipopolysaccharide.Mito-xenophagic killing of bacteria is coordinated by a metabolic switch in dendritic cellsExpression and function of phospholipase A(2) in brain.Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in brain of HIV-1 transgenic ratsEffect of polyunsaturated fatty acids on drug-sensitive and resistant tumor cells in vitroPhospholipase A2 in the central nervous system: implications for neurodegenerative diseases.Low-dose aspirin (acetylsalicylate) prevents increases in brain PGE2, 15-epi-lipoxin A4 and 8-isoprostane concentrations in 9 month-old HIV-1 transgenic rats, a model for HIV-1 associated neurocognitive disorders.Neuroinflammation and synaptic lossAging is associated with altered inflammatory, arachidonic acid cascade, and synaptic markers, influenced by epigenetic modifications, in the human frontal cortex.Integration of cytokine biology and lipid metabolism in strokeRETRACTED: Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in the postmortem frontal cortex from schizophrenia patientsMinocycline targets multiple secondary injury mechanisms in traumatic spinal cord injury.4-Hydroxy-2-nonenal upregulates and phosphorylates cytosolic phospholipase A(2) in cultured Ra2 microglial cells via MAPK pathways.FcgammaR receptors activate MAP kinase and up-regulate the cyclooxygenase pathway without increasing arachidonic acid release in monocytic cells.Inflammatory cytokines enhance muscarinic-mediated arachidonic acid release through p38 mitogen-activated protein kinase in A2058 cells.Inhibition of cPLA2 activation by Ginkgo biloba extract protects spinal cord neurons from glutamate excitotoxicity and oxidative stress-induced cell death.Gabapentin Attenuates Ocular Inflammation: In vitro and In vivo Studies.Atypical lambda/iota PKC conveys 5-lipoxygenase/leukotriene B4-mediated cross-talk between phospholipase A2s regulating NF-kappa B activation in response to tumor necrosis factor-alpha and interleukin-1beta.Phosphorylation of p42/44(MAPK) by various signal transduction pathways activates cytosolic phospholipase A(2) to variable degrees.Functional coupling between secretory and cytosolic phospholipase A2 modulates tumor necrosis factor-alpha- and interleukin-1beta-induced NF-kappa B activation.Plausible role of naringenin against cerebrally implanted C6 glioma cells in rats.Alcohol-induced neurodegeneration: when, where and why?p38 MAPK and NF-kappaB on IL-6 release in human gingival fibroblasts.RhoA/Rho Kinase Mediates Neuronal Death Through Regulating cPLA2 Activation.Epigenetic Regulation of Cytosolic Phospholipase A2 in SH-SY5Y Human Neuroblastoma Cells.Insights into abnormal sphingolipid metabolism in multiple sclerosis: targeting ceramide biosynthesis as a unique therapeutic strategy.
P2860
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P2860
Signaling mechanisms involved in the activation of arachidonic acid metabolism in human astrocytoma cells by tumor necrosis factor-alpha: phosphorylation of cytosolic phospholipase A2 and transactivation of cyclooxygenase-2.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Signaling mechanisms involved ...... ctivation of cyclooxygenase-2.
@en
Signaling mechanisms involved ...... ctivation of cyclooxygenase-2.
@nl
type
label
Signaling mechanisms involved ...... ctivation of cyclooxygenase-2.
@en
Signaling mechanisms involved ...... ctivation of cyclooxygenase-2.
@nl
prefLabel
Signaling mechanisms involved ...... ctivation of cyclooxygenase-2.
@en
Signaling mechanisms involved ...... ctivation of cyclooxygenase-2.
@nl
P2860
P50
P1476
Signaling mechanisms involved ...... ctivation of cyclooxygenase-2.
@en
P2860
P304
P356
10.1046/J.1471-4159.1999.0731641.X
P407
P577
1999-10-01T00:00:00Z