D-serine augments NMDA-NR2B receptor-dependent hippocampal long-term depression and spatial reversal learning.
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Mutation I810N in the alpha3 isoform of Na+,K+-ATPase causes impairments in the sodium pump and hyperexcitability in the CNS.Role for neonatal D-serine signaling: prevention of physiological and behavioral deficits in adult Pick1 knockout mice.Specific downregulation of hippocampal ATF4 reveals a necessary role in synaptic plasticity and memoryType VI adenylyl cyclase negatively regulates GluN2B-mediated LTD and spatial reversal learning.Neuroplasticity regulation by noradrenaline in mammalian brainBehavioural phenotyping assays for mouse models of autism1-aminocyclopropanecarboxylic acid (ACPC) produces procognitive but not antipsychotic-like effects in rats.Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice.Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model.Criteria for validating mouse models of psychiatric diseasesFear memory impairing effects of systemic treatment with the NMDA NR2B subunit antagonist, Ro 25-6981, in mice: attenuation with ageingmGluR5 has a critical role in inhibitory learning.Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning.Fluctuations in endogenous kynurenic acid control hippocampal glutamate and memoryLRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype.GluN2B in corticostriatal circuits governs choice learning and choice shifting.Benchmark IV Progressing Nicely: Rational Pharmacotherapy May Address Cognitive Decline in Epilepsy.Long-term potentiation depends on release of D-serine from astrocytes.Identification of postsynaptic phosphatidylinositol-4,5-bisphosphate (PIP2) roles for synaptic plasticity using chemically induced dimerizationExpression of the NR2B-NMDA receptor trafficking complex in prefrontal cortex from a group of elderly patients with schizophrenia.Once-weekly D-cycloserine effects on negative symptoms and cognition in schizophrenia: an exploratory study.D-cycloserine facilitation of cognitive behavioral therapy for delusions in schizophrenia.D-serine treatment reduces cocaine-primed reinstatement in rats following extended access to cocaine self-administration.Modulation of synaptic plasticity by stress hormone associates with plastic alteration of synaptic NMDA receptor in the adult hippocampus.Organization, control and function of extrasynaptic NMDA receptors.The NMDA receptor as a target for cognitive enhancementDeletion of glutamate delta-1 receptor in mouse leads to enhanced working memory and deficit in fear conditioning.Roles of p75(NTR), long-term depression, and cholinergic transmission in anxiety and acute stress copingStress-induced impairments in prefrontal-mediated behaviors and the role of the N-methyl-D-aspartate receptor.Motor-Skill Learning Is Dependent on Astrocytic Activity.Osmotic Edema Rapidly Increases Neuronal Excitability Through Activation of NMDA Receptor-Dependent Slow Inward Currents in Juvenile and Adult HippocampusComparing the predictive value of multiple cognitive, affective, and motor tasks after rodent traumatic brain injury.Gestational methylazoxymethanol exposure leads to NMDAR dysfunction in hippocampus during early development and lasting deficits in learningMemory in aged mice is rescued by enhanced expression of the GluN2B subunit of the NMDA receptor.d-amino acid oxidase knockout (Dao(-/-) ) mice show enhanced short-term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption.Genetic, pharmacological and lesion analyses reveal a selective role for corticohippocampal GLUN2B in a novel repeated swim stress paradigm.Long-term potentiation of synaptic transmission in the adult mouse insular cortex: multielectrode array recordings.Genetic inactivation of D-amino acid oxidase enhances extinction and reversal learning in miceD-serine increases adult hippocampal neurogenesis.The context dependency of extinction negates the effectiveness of cognitive enhancement to reduce cocaine-primed reinstatement.
P2860
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P2860
D-serine augments NMDA-NR2B receptor-dependent hippocampal long-term depression and spatial reversal learning.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
D-serine augments NMDA-NR2B re ...... and spatial reversal learning.
@en
D-serine augments NMDA-NR2B re ...... and spatial reversal learning.
@nl
type
label
D-serine augments NMDA-NR2B re ...... and spatial reversal learning.
@en
D-serine augments NMDA-NR2B re ...... and spatial reversal learning.
@nl
prefLabel
D-serine augments NMDA-NR2B re ...... and spatial reversal learning.
@en
D-serine augments NMDA-NR2B re ...... and spatial reversal learning.
@nl
P2093
P2860
P356
P1476
D-serine augments NMDA-NR2B re ...... and spatial reversal learning.
@en
P2093
John C Roder
Steven Duffy
Viviane Labrie
P2860
P2888
P304
P356
10.1038/SJ.NPP.1301486
P407
P577
2007-07-11T00:00:00Z