Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
about
Structural basis of Notch O-glucosylation and O-xylosylation by mammalian protein-O-glucosyltransferase 1 (POGLUT1).Variant in human POFUT1 reduces enzymatic activity and likely causes a recessive microcephaly, global developmental delay with cardiac and vascular features.POFUT1 promotes colorectal cancer development through the activation of Notch1 signaling
P2860
Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
description
2017 nî lūn-bûn
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2017年の論文
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2017年学术文章
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2017年学术文章
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2017年学术文章
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2017年学术文章
@zh-my
2017年学术文章
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2017年學術文章
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2017年學術文章
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2017年學術文章
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name
Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
@en
Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
@nl
type
label
Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
@en
Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
@nl
prefLabel
Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
@en
Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
@nl
P2093
P2860
P356
P1476
Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1.
@en
P2093
Dongxia Zhou
James M Rini
John E Pak
Kristina Han
Malathy Satkunarajah
P2860
P2888
P304
P356
10.1038/NCHEMBIO.2381
P50
P577
2017-05-22T00:00:00Z
P6179
1085460160