Reduced GABAergic inhibition explains cortical hyperexcitability in the wobbler mouse model of ALS.
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VPS54 and the wobbler mouseMultimodal MRI as a diagnostic biomarker for amyotrophic lateral sclerosisThe Wobbler mouse model of amyotrophic lateral sclerosis (ALS) displays hippocampal hyperexcitability, and reduced number of interneurons, but no presynaptic vesicle release impairments.An imbalance between excitatory and inhibitory neurotransmitters in amyotrophic lateral sclerosis revealed by use of 3-T proton magnetic resonance spectroscopy.Decreased motor cortex γ-aminobutyric acid in amyotrophic lateral sclerosis.The wobbler mouse, an ALS animal model.Altered cortical beta-band oscillations reflect motor system degeneration in amyotrophic lateral sclerosis.Impairments in Motor Neurons, Interneurons and Astrocytes Contribute to Hyperexcitability in ALS: Underlying Mechanisms and Paths to Therapy.Syphilis may be a confounding factor, not a causative agent, in syphilitic ALS.Metabolic Dysfunctions in Amyotrophic Lateral Sclerosis Pathogenesis and Potential Metabolic TreatmentsAltered Functionality, Morphology, and Vesicular Glutamate Transporter Expression of Cortical Motor Neurons from a Presymptomatic Mouse Model of Amyotrophic Lateral Sclerosis.Loss of vps54 function leads to vesicle traffic impairment, protein mis-sorting and embryonic lethality.Progesterone attenuates several hippocampal abnormalities of the Wobbler mouse.Progesterone prevents mitochondrial dysfunction in the spinal cord of wobbler mice.Examining alterations in GABA concentrations in the basal ganglia of patients with Parkinson's disease using MEGA-PRESS MRS.
P2860
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P2860
Reduced GABAergic inhibition explains cortical hyperexcitability in the wobbler mouse model of ALS.
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2010 nî lūn-bûn
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2010年の論文
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name
Reduced GABAergic inhibition e ...... he wobbler mouse model of ALS.
@en
Reduced GABAergic inhibition e ...... he wobbler mouse model of ALS.
@nl
type
label
Reduced GABAergic inhibition e ...... he wobbler mouse model of ALS.
@en
Reduced GABAergic inhibition e ...... he wobbler mouse model of ALS.
@nl
prefLabel
Reduced GABAergic inhibition e ...... he wobbler mouse model of ALS.
@en
Reduced GABAergic inhibition e ...... he wobbler mouse model of ALS.
@nl
P2093
P2860
P356
P1433
P1476
Reduced GABAergic inhibition e ...... he wobbler mouse model of ALS.
@en
P2093
Jakob Moser
Kimmo Jensen
Thomas Schmitt-John
P2860
P304
P356
10.1093/CERCOR/BHQ134
P577
2010-07-19T00:00:00Z