Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2.

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Bacterial Derived Carbohydrates Bind Cyr1 and Trigger Hyphal Growth in Candida albicans.Crohn's Disease Variants of Nod2 Are Stabilized by the Critical Contact Region of Hsp70.

P2860

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Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2.

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http://www.wikidata.org/entity/Q48124216

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Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2.

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Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2.

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Item

label

Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2.

@en

Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2.

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Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2.

@en

Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2.

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P1476

Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2.

@en

P2093

Amy K Schaefer

http://www.w3.org/2001/XMLSchema#string

James E Melnyk

http://www.w3.org/2001/XMLSchema#string

Klare M Lazor

http://www.w3.org/2001/XMLSchema#string

Michael M Baksh

http://www.w3.org/2001/XMLSchema#string

P2860

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

The molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn disease

NLRs join TLRs as innate sensors of pathogens

Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition

Innate immune recognition

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1α, controlling necrosis-induced sterile inflammation

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2216-2224

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P31

scholarly article

P356

10.1021/ACSCHEMBIO.7B00469

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

M G Finn

Catherine L Grimes

P577

2017-07-25T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28708377

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P932

5569645

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Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2.

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P2860

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Membrane Association Dictates Ligand Specificity for the Innate Immune Receptor NOD2.

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932