Carnosine inhibits Aβ(42) aggregation by perturbing the H-bond network in and around the central hydrophobic cluster.
about
Carnosinases, their substrates and diseasesMolecular mechanisms of disease-causing missense mutationsPhysiology and pathophysiology of carnosine.The Chemistry of Neurodegeneration: Kinetic Data and Their Implications.The conserved lid tryptophan, W211, potentiates thermostability and thermoactivity in bacterial thermoalkalophilic lipasesOn the Relationship between Energy Metabolism, Proteostasis, Aging and Parkinson's Disease: Possible Causative Role of Methylglyoxal and Alleviative Potential of Carnosine.Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies.Pathological unfoldomics of uncontrolled chaos: intrinsically disordered proteins and human diseasesCarnosine's effect on amyloid fibril formation and induced cytotoxicity of lysozyme.Brazilin inhibits amyloid β-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicity.Identification of inhibitors of biological interactions involving intrinsically disordered proteins.The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments.Combined experimental and simulation studies suggest a revised mode of action of the anti-Alzheimer disease drug NQ-Trp.Effects of Zn2+ binding on the structural and dynamic properties of amyloid β peptide associated with Alzheimer's disease: Asp1 or Glu11?Atomic and dynamic insights into the beneficial effect of the 1,4-naphthoquinon-2-yl-L-tryptophan inhibitor on Alzheimer's Aβ1-42 dimer in terms of aggregation and toxicity.Strategy to discover full-length amyloid-beta peptide ligands using high-efficiency microarray technology.Comparison of Kinetic Study and Protective Effects of Biological Dipeptide and Two Porphyrin Derivatives on Metal Cytotoxicity Toward Human Lymphocytes.Zinc, Carnosine, and Neurodegenerative Diseases.Inhibition of Prion Propagation by 3,4-Dimethoxycinnamic Acid.
P2860
Q26829095-1F13C8BC-5428-4A66-AF59-9389FD339868Q27021940-4C128B8A-0AA9-45B9-8C10-225FC6414DD4Q27692648-4B56C486-9F4C-4A31-8FC0-3AEDCA49E45FQ30973484-1F36CFED-EAF8-4AD5-A812-0A7FC983C521Q31147221-3D1B3104-C839-4FEB-82D0-D42A76E6E8F4Q33714263-B464F69D-17ED-4254-BE0A-C16EB640FB05Q33893017-9D02F595-5353-463B-92F5-3019FD720E58Q33909288-E73A301C-28CE-4660-B29E-E1ABE8982077Q35069891-B1E201BA-9FFF-4CD7-9CBB-8E81A468AA22Q35547479-00970940-682B-4C98-9876-7150283672B9Q35585498-96E9A4AF-CF32-4A77-B557-01EF706F03F2Q36205942-E8A308E6-B47D-47C9-A5FE-E0EDFA215272Q40732132-CE28226F-8296-4F70-9AA3-AC08AA6238D8Q41913386-C3F4431E-D5BC-4D7F-BE14-6BEB5B9DC735Q41969921-A6F86054-3C6B-48D9-A018-FFB0AA005847Q46242478-43051E8A-C9BC-43D3-8BDB-582FF5425719Q47136945-354A48C0-F6AA-4653-A372-B3AFD85D332AQ47831358-721487BE-AEA0-4C90-98BF-5A7D17ECE766Q48137576-2D6F8143-BE71-4007-A4A1-59F1B0772F3A
P2860
Carnosine inhibits Aβ(42) aggregation by perturbing the H-bond network in and around the central hydrophobic cluster.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh
2013年學術文章
@zh-hant
name
Carnosine inhibits Aβ
@nl
Carnosine inhibits Aβ(42) aggr ...... e central hydrophobic cluster.
@en
type
label
Carnosine inhibits Aβ
@nl
Carnosine inhibits Aβ(42) aggr ...... e central hydrophobic cluster.
@en
prefLabel
Carnosine inhibits Aβ
@nl
Carnosine inhibits Aβ(42) aggr ...... e central hydrophobic cluster.
@en
P2093
P2860
P50
P356
P1433
P1476
Carnosine inhibits Aβ(42) aggr ...... e central hydrophobic cluster.
@en
P2093
Amedeo Caflisch
Andrea Magno
Bruno Pignataro
Enrico Rizzarelli
Gennaro Esposito
Haritha Haridas
Marino Convertino
P2860
P304
P356
10.1002/CBIC.201200704
P577
2013-02-25T00:00:00Z