Pyrrolidine dithiocarbamate activates Akt and improves spatial learning in APP/PS1 mice without affecting beta-amyloid burden.
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(-)-SCR1693 Protects against Memory Impairment and Hippocampal Damage in a Chronic Cerebral Hypoperfusion Rat ModelSpines, plasticity, and cognition in Alzheimer's model miceImpact of pyrrolidine dithiocarbamate and interleukin-6 on mammalian target of rapamycin complex 1 regulation and global protein translationTowards understanding brain-gut-microbiome connections in Alzheimer's diseasePyrrolidine dithiocarbamate attenuates brain Aβ increase and improves long-term neurological outcome in rats after transient focal brain ischemia.Lipopolysaccharides up-regulate Kir6.1/SUR2B channel expression and enhance vascular KATP channel activity via NF-kappaB-dependent signalingc-Jun N-terminal kinase has a key role in Alzheimer disease synaptic dysfunction in vivo.RanBP9 overexpression accelerates loss of dendritic spines in a mouse model of Alzheimer's diseaseIn vivo and in vitro effects of an apolipoprotein e mimetic peptide on amyloid-β pathologyPharmacological and genetic reversal of age-dependent cognitive deficits attributable to decreased presenilin functionHuman intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's diseaseSynaptic changes in the dentate gyrus of APP/PS1 transgenic mice revealed by electron microscopy.Aberrant detergent-insoluble excitatory amino acid transporter 2 accumulates in Alzheimer disease.GSK-3 in Neurodegenerative Diseases.Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer's disease.Neuroprotective copper bis(thiosemicarbazonato) complexes promote neurite elongation.Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis.Copper modulation as a therapy for Alzheimer's disease?Sildenafil restores cognitive function without affecting β-amyloid burden in a mouse model of Alzheimer's disease.SCM-198 Ameliorates Cognitive Deficits, Promotes Neuronal Survival and Enhances CREB/BDNF/TrkB Signaling without Affecting Aβ Burden in AβPP/PS1 Mice.Identification of novel genes that modify phenotypes induced by Alzheimer's beta-amyloid overexpression in DrosophilaPyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes.Free radical-mediated damage to brain in Alzheimer's disease and its transgenic mouse models.Abnormal Population Responses in the Somatosensory Cortex of Alzheimer's Disease Model Mice.The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer's disease.Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosisIncreasing Cu bioavailability inhibits Abeta oligomers and tau phosphorylation.Detergent-insoluble EAAC1/EAAT3 aberrantly accumulates in hippocampal neurons of Alzheimer's disease patients.Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease.Neuroendocrine immunomodulation network dysfunction in SAMP8 mice and PrP-hAβPPswe/PS1ΔE9 mice: potential mechanism underlying cognitive impairment.Pharmacotherapeutic targets in Alzheimer's diseaseIntrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease.Metallo-complex activation of neuroprotective signalling pathways as a therapeutic treatment for Alzheimer's disease.Cyp1B1 expression promotes angiogenesis by suppressing NF-κB activity.Susceptibility to focal and global brain ischemia of Alzheimer mice displaying aβ deposits: effect of immunoglobulinIntravenous ascorbate improves spatial memory in middle-aged APP/PSEN1 and wild type mice.The iron regulatory capability of the major protein participants in prevalent neurodegenerative disorders.Targeting Glycogen Synthase Kinase-3β for Therapeutic Benefit against Oxidative Stress in Alzheimer's Disease: Involvement of the Nrf2-ARE Pathway.Glycogen synthase kinase-3β: a mediator of inflammation in Alzheimer's disease?Metal attenuating therapies in neurodegenerative disease.
P2860
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P2860
Pyrrolidine dithiocarbamate activates Akt and improves spatial learning in APP/PS1 mice without affecting beta-amyloid burden.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Pyrrolidine dithiocarbamate ac ...... affecting beta-amyloid burden.
@en
Pyrrolidine dithiocarbamate ac ...... affecting beta-amyloid burden.
@nl
type
label
Pyrrolidine dithiocarbamate ac ...... affecting beta-amyloid burden.
@en
Pyrrolidine dithiocarbamate ac ...... affecting beta-amyloid burden.
@nl
prefLabel
Pyrrolidine dithiocarbamate ac ...... affecting beta-amyloid burden.
@en
Pyrrolidine dithiocarbamate ac ...... affecting beta-amyloid burden.
@nl
P2093
P1476
Pyrrolidine dithiocarbamate ac ...... affecting beta-amyloid burden.
@en
P2093
Antero Salminen
Gundars Goldsteins
Heikki Tanila
Henna Iivonen
Jari Koistinaho
Katja Kanninen
Seppo Auriola
Thomas Van Groen
Toni Ahtoniemi
Velta Keksa-Goldsteine
P304
P356
10.1523/JNEUROSCI.0059-07.2007
P407
P50
P577
2007-04-01T00:00:00Z