SAS-4 is essential for centrosome duplication in C elegans and is recruited to daughter centrioles once per cell cycle.
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Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerPolo-like kinase 4: the odd one out of the familyBasal body stability and ciliogenesis requires the conserved component Poc1The human microcephaly protein STIL interacts with CPAP and is required for procentriole formationCentrobin-tubulin interaction is required for centriole elongation and stabilityPLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycleHuman microcephaly protein CEP135 binds to hSAS-6 and CPAP, and is required for centriole assemblyTankyrase 1 regulates centrosome function by controlling CPAP stabilitySAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cellsThe hydrolethalus syndrome protein HYLS-1 links core centriole structure to cilia formationNEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assemblyBuilding a ninefold symmetrical barrel: structural dissections of centriole assemblySAS-1 is a C2 domain protein critical for centriole integrity in C. elegansStructural Basis of the 9-Fold Symmetry of CentriolesSAS-6 coiled-coil structure and interaction with SAS-5 suggest a regulatory mechanism inC. eleganscentriole assemblyCaenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry.Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephalyStructural Analysis of the G-Box Domain of the Microcephaly Protein CPAP Suggests a Role in Centriole ArchitectureSas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosomeAcentriolar mitosis activates a p53-dependent apoptosis pathway in the mouse embryoCell cycle regulators control centrosome elimination during oogenesis in Caenorhabditis elegans.SAS-4 is recruited to a dynamic structure in newly forming centrioles that is stabilized by the gamma-tubulin-mediated addition of centriolar microtubules.Control of mitotic and meiotic centriole duplication by the Plk4-related kinase ZYG-1Overly long centrioles and defective cell division upon excess of the SAS-4-related protein CPAP.Analysis of centriole elimination during C. elegans oogenesis.A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila.The origin of the second centriole in the zygote of Drosophila melanogasterDimerization of CPAP orchestrates centrosome cohesion plasticity.Drosophila Ana2 is a conserved centriole duplication factorAutophosphorylation of polo-like kinase 4 and its role in centriole duplicationThe conserved protein SZY-20 opposes the Plk4-related kinase ZYG-1 to limit centrosome size.Centrioles initiate cilia assembly but are dispensable for maturation and maintenance in C. elegans.The elegans of spindle assembly.Centrioles: active players or passengers during mitosis?The centriole duplication cycle.Causes and consequences of centrosome abnormalities in cancer.Formation of extra centrosomal structures is dependent on beta-catenin.Reconstructing the evolutionary history of the centriole from protein components.Building the centriole.Cep120 is asymmetrically localized to the daughter centriole and is essential for centriole assembly.
P2860
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P2860
SAS-4 is essential for centrosome duplication in C elegans and is recruited to daughter centrioles once per cell cycle.
description
2003 nî lūn-bûn
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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name
SAS-4 is essential for centros ...... entrioles once per cell cycle.
@en
SAS-4 is essential for centros ...... entrioles once per cell cycle.
@nl
type
label
SAS-4 is essential for centros ...... entrioles once per cell cycle.
@en
SAS-4 is essential for centros ...... entrioles once per cell cycle.
@nl
prefLabel
SAS-4 is essential for centros ...... entrioles once per cell cycle.
@en
SAS-4 is essential for centros ...... entrioles once per cell cycle.
@nl
P1433
P1476
SAS-4 is essential for centros ...... entrioles once per cell cycle.
@en
P2093
Pierre Gönczy
P304
P356
10.1016/S1534-5807(03)00062-5
P407
P577
2003-03-01T00:00:00Z