Isolated central nervous system relapse in patient with blast-crisis chronic myeloid leukemia in durable complete cytogenetic remission on dasatinib treatment: pharmacokinetics and ABL mutation analysis in cerebrospinal fluid.

Isolated central nervous system relapse in patient with blast-crisis chronic myeloid leukemia in durable complete cytogenetic remission on dasatinib treatment: pharmacokinetics and ABL mutation analysis in cerebrospinal fluid.

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Q48274819

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Pharmacokinetic Properties of Anticancer Agents for the Treatment of Central Nervous System Tumors: Update of the Literature.Oxidation of KCNB1 channels in the human brain and in mouse model of Alzheimer's disease

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Isolated central nervous system relapse in patient with blast-crisis chronic myeloid leukemia in durable complete cytogenetic remission on dasatinib treatment: pharmacokinetics and ABL mutation analysis in cerebrospinal fluid.

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http://www.wikidata.org/entity/Q48274819

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2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年学术文章

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2012年學術文章

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2012年學術文章

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name

Isolated central nervous syste ...... alysis in cerebrospinal fluid.

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Isolated central nervous syste ...... alysis in cerebrospinal fluid.

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Isolated central nervous syste ...... alysis in cerebrospinal fluid.

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Isolated central nervous syste ...... alysis in cerebrospinal fluid.

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Isolated central nervous syste ...... alysis in cerebrospinal fluid.

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Isolated central nervous syste ...... alysis in cerebrospinal fluid.

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P1476

Isolated central nervous syste ...... alysis in cerebrospinal fluid.

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P2093

Changxin Yin

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Fanyi Meng

http://www.w3.org/2001/XMLSchema#string

Hong-Sheng Zhou

http://www.w3.org/2001/XMLSchema#string

Min Dai

http://www.w3.org/2001/XMLSchema#string

Na Xu

http://www.w3.org/2001/XMLSchema#string

Qiang Wang

http://www.w3.org/2001/XMLSchema#string

Yongqiang Wei

http://www.w3.org/2001/XMLSchema#string

P2860

First report of phase 2 study of dasatinib with hyper-CVAD for the frontline treatment of patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia.

Discovery of 3-[2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a potent, orally active pan-inhibitor of breakpoint cluster region-abelson (BCR-ABL) kinase includ

Dasatinib in imatinib-resistant or imatinib-intolerant chronic myeloid leukemia in blast phase after 2 years of follow-up in a phase 3 study: efficacy and tolerability of 140 milligrams once daily and 70 milligrams twice daily.

Central nervous system is a sanctuary site for chronic myelogenous leukaemia treated with imatinib mesylate.

Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia

Ponatinib is active against imatinib-resistant mutants of FIP1L1-PDGFRA and KIT, and against FGFR1-derived fusion kinases.

Low concentrations of STI571 in the cerebrospinal fluid: a case report.

Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment.

Central nervous system failure in patients with chronic myelogenous leukemia lymphoid blast crisis and Philadelphia chromosome positive acute lymphoblastic leukemia treated with imatinib (STI-571).

INNO-406, a novel BCR-ABL/Lyn dual tyrosine kinase inhibitor, suppresses the growth of Ph+ leukemia cells in the central nervous system, and cyclosporine A augments its in vivo activity.

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1557-1559

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scholarly article

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10.3109/10428194.2012.745933

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2012-12-22T00:00:00Z

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23194002

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P921

cerebrospinal fluid

chronic myeloid leukemia

Isolated central nervous system relapse in patient with blast-crisis chronic myeloid leukemia in durable complete cytogenetic remission on dasatinib treatment: pharmacokinetics and ABL mutation analysis in cerebrospinal fluid.

about

P2860

P2860

Isolated central nervous system relapse in patient with blast-crisis chronic myeloid leukemia in durable complete cytogenetic remission on dasatinib treatment: pharmacokinetics and ABL mutation analysis in cerebrospinal fluid.

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