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Cellular and Molecular Pathology of Age-Related Macular Degeneration: Potential Role for ProteoglycansAtherogenic, fibrotic and glucose utilising actions of glucokinase activators on vascular endothelium and smooth musclePlatelet-derived growth factor differentially regulates the expression and post-translational modification of versican by arterial smooth muscle cells through distinct protein kinase C and extracellular signal-regulated kinase pathwaysLOX-1 in atherosclerosis: biological functions and pharmacological modifiers.The nerve growth factor signaling and its potential as therapeutic target for glaucomaImatinib inhibits vascular smooth muscle proteoglycan synthesis and reduces LDL binding in vitro and aortic lipid deposition in vivo.Stereoselective reduction of 1-o-isopropyloxygenipin enhances its neuroprotective activity in neuronal cells from apoptosis induced by sodium nitroprusside.IGF-1 signaling via the PI3K/Akt pathway confers neuroprotection in human retinal pigment epithelial cells exposed to sodium nitroprusside insult.Genetic and physiological association of diabetes susceptibility with raised Na+/H+ exchange activity.Lithium ions attenuate serum-deprivation-induced apoptosis in PC12 cells through regulation of the Akt/FoxO1 signaling pathways.Thrombin-mediated proteoglycan synthesis utilizes both protein-tyrosine kinase and serine/threonine kinase receptor transactivation in vascular smooth muscle cells.Clinical thiazolidinediones as PPARgamma ligands with the potential for the prevention of cardiovascular disease in diabetes.Endothelin-1 signalling in vascular smooth muscle: pathways controlling cellular functions associated with atherosclerosis.Multiple Growth Factors, But Not VEGF, Stimulate Glycosaminoglycan Hyperelongation in Retinal Choroidal Endothelial Cells.Tanshinone IIA suppresses cholesterol accumulation in human macrophages: role of heme oxygenase-1.Smad linker region phosphorylation in the regulation of extracellular matrix synthesis.Transforming growth factor-β regulation of proteoglycan synthesis in vascular smooth muscle: contribution to lipid binding and accelerated atherosclerosis in diabetes.Zinc and cardiovascular disease.G protein coupled receptor transactivation: extending the paradigm to include serine/threonine kinase receptors.Forkhead family transcription factor FoxO and neural differentiation.The possible role of the Akt signaling pathway in schizophrenia.Therapeutic implications of endothelin and thrombin G-protein-coupled receptor transactivation of tyrosine and serine/threonine kinase cell surface receptors.GPCR responses in vascular smooth muscle can occur predominantly through dual transactivation of kinase receptors and not classical Gαq protein signalling pathways.Transforming growth factor-β signalling: role and consequences of Smad linker region phosphorylation.Poly(ADP-ribose) polymerase 1 (PARP1) in atherosclerosis: from molecular mechanisms to therapeutic implications.The status of radioimmunotherapy in CD20+ non-Hodgkin's lymphoma.Peptidyl-prolyl isomerases: functionality and potential therapeutic targets in cardiovascular disease.The expansion of GPCR transactivation-dependent signalling to include serine/threonine kinase receptors represents a new cell signalling frontier.The role of specific Smad linker region phosphorylation in TGF-β mediated expression of glycosaminoglycan synthesizing enzymes in vascular smooth muscle.Forkhead box O transcription factors as possible mediators in the development of major depression.Elucidating the role of the FoxO3a transcription factor in the IGF-1-induced migration and invasion of uveal melanoma cancer cells.Insights into cellular signalling by G protein coupled receptor transactivation of cell surface protein kinase receptors.The emerging role of metformin in gestational diabetes mellitus.Gaq proteins: molecular pharmacology and therapeutic potential.Atheroprotective Effects and Molecular Targets of Tanshinones Derived From Herbal Medicine Danshen.Animal models for assessing the impact of natural products on the aetiology and metabolic pathophysiology of Type 2 diabetes.Amiodarone-Induced Retinal Neuronal Cell Apoptosis Attenuated by IGF-1 via Counter Regulation of the PI3k/Akt/FoxO3a Pathway.Tanshinone II-A inhibits oxidized LDL-induced LOX-1 expression in macrophages by reducing intracellular superoxide radical generation and NF-κB activation.Insulin-like growth factor-1 induces the phosphorylation of PRAS40 via the PI3K/Akt signaling pathway in PC12 cells.The Atypical Antipsychotic Agent, Clozapine, Protects Against Corticosterone-Induced Death of PC12 Cells by Regulating the Akt/FoxO3a Signaling Pathway.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Peter J Little
@ast
Peter J Little
@en
Peter J Little
@es
Peter J Little
@nl
Peter J Little
@sl
type
label
Peter J Little
@ast
Peter J Little
@en
Peter J Little
@es
Peter J Little
@nl
Peter J Little
@sl
prefLabel
Peter J Little
@ast
Peter J Little
@en
Peter J Little
@es
Peter J Little
@nl
Peter J Little
@sl
P1053
F-9865-2015
P106
P21
P31
P3829
P496
0000-0002-0335-3835
P569
2000-01-01T00:00:00Z