Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

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Taccalonolide Microtubule Stabilizers Generated Using Semisynthesis Define the Effects of Mono Acyloxy Moieties at C-7 or C-15 and Disubstitutions at C-7 and C-25.

P2860

Q48185206-CC049D14-4E36-4CCD-A856-D0364A86D0D2

P2860

Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

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http://www.wikidata.org/entity/Q48324408

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2017 nî lūn-bûn

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2017年の論文

@ja

2017年学术文章

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2017年学术文章

@zh

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

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Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

@en

Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

@nl

type

Item

label

Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

@en

Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

@nl

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Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

@en

Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

@nl

P1476

Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

@en

P2093

Andrew J Robles

http://www.w3.org/2001/XMLSchema#string

Jing Li

http://www.w3.org/2001/XMLSchema#string

John G Kuhn

http://www.w3.org/2001/XMLSchema#string

Lin Du

http://www.w3.org/2001/XMLSchema#string

Raymond Benavides

http://www.w3.org/2001/XMLSchema#string

Susan L Mooberry

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P2860

Taccalonolide microtubule stabilizers

Molecular mechanism of action of microtubule-stabilizing anticancer agents

New colorimetric cytotoxicity assay for anticancer-drug screening

Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules

Microtubule-stabilizing drugs from marine sponges: focus on peloruside A and zampanolide

Synthetic reactions with rare taccalonolides reveal the value of C-22,23 epoxidation for microtubule stabilizing potency.

Brentuximab vedotin for relapsed or refractory Hodgkin's lymphoma.

Identification and biological activities of new taccalonolide microtubule stabilizers.

A unique mode of microtubule stabilization induced by peloruside A

The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms.

P304

409-414

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P31

scholarly article

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10.1021/ACS.JNATPROD.6B00944

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

April L Risinger

Robert H Cichewicz

P577

2017-01-23T00:00:00Z

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P698

28112516

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P932

5553283

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Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

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P2860

P2860

Pharmacokinetic Analysis and in Vivo Antitumor Efficacy of Taccalonolides AF and AJ.

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932