Mice deficient in group IV cytosolic phospholipase A2 are resistant to MPTP neurotoxicity.
about
Role of prostaglandins in neuroinflammatory and neurodegenerative diseasesCytosolic phospholipase A2 alpha inhibition prevents neuronal NMDA receptor-stimulated arachidonic acid mobilization and prostaglandin production but not subsequent cell death.Arachidonic acid metabolism in brain physiology and pathology: lessons from genetically altered mouse modelsRole of secretory phospholipase a(2) in CNS inflammation: implications in traumatic spinal cord injury.Purification and characterization of a cytosolic Ca(2+)-independent phospholipase A(2) from bovine brain.Cytosolic phospholipase A2 alpha amplifies early cyclooxygenase-2 expression, oxidative stress and MAP kinase phosphorylation after cerebral ischemia in mice.Cytosolic phospholipase A2 protein as a novel therapeutic target for spinal cord injurySevere alterations in lipid composition of frontal cortex lipid rafts from Parkinson's disease and incidental Parkinson's disease.Cytosolic phospholipase A(2) alpha mediates electrophysiologic responses of hippocampal pyramidal neurons to neurotoxic NMDA treatmentCytosolic phospholipase A₂: physiological function and role in disease.cPLA(2)α gene activation by IL-1β is dependent on an upstream kinase pathway, enzymatic activation and downstream 15-lipoxygenase activity: a positive feedback loopDiscrete role for cytosolic phospholipase A(2)alpha in platelets: studies using single and double mutant mice of cytosolic and group IIA secretory phospholipase A(2).Characterization of eicosanoid synthesis in a genetic ablation model of ceramide kinaseDenervation induces cytosolic phospholipase A2-mediated fatty acid hydroperoxide generation by muscle mitochondriaThe biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's diseaseα-Synuclein-induced synapse damage in cultured neurons is mediated by cholesterol-sensitive activation of cytoplasmic phospholipase A2.Lipid-mediated oxidative stress and inflammation in the pathogenesis of Parkinson's disease.
P2860
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P2860
Mice deficient in group IV cytosolic phospholipase A2 are resistant to MPTP neurotoxicity.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Mice deficient in group IV cyt ...... sistant to MPTP neurotoxicity.
@en
Mice deficient in group IV cyt ...... sistant to MPTP neurotoxicity.
@nl
type
label
Mice deficient in group IV cyt ...... sistant to MPTP neurotoxicity.
@en
Mice deficient in group IV cyt ...... sistant to MPTP neurotoxicity.
@nl
prefLabel
Mice deficient in group IV cyt ...... sistant to MPTP neurotoxicity.
@en
Mice deficient in group IV cyt ...... sistant to MPTP neurotoxicity.
@nl
P2093
P1476
Mice deficient in group IV cytosolic phospholipase A2 are resistant to MPTP neurotoxicity
@en
P2093
J V Bonventre
P Klivenyi
R J Ferrante
P304
P356
10.1046/J.1471-4159.1998.71062634.X
P407
P577
1998-12-01T00:00:00Z