Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.
about
Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brainPKA modulates GSK-3beta- and cdk5-catalyzed phosphorylation of tau in site- and kinase-specific mannersMechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2(PP2A)/SETPresenilin 1 associates with glycogen synthase kinase-3beta and its substrate tauTau protein binds to microtubules through a flexible array of distributed weak sitesDual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusionRegulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegenerationTherapeutic benefits of a component of coffee in a rat model of Alzheimer's disease.Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filamentsCloning and sequencing of the cDNA encoding a core protein of the paired helical filament of Alzheimer disease: identification as the microtubule-associated protein tauHyperphosphorylation of microtubule-associated protein tau: a promising therapeutic target for Alzheimer diseaseNeuropathology of non-Alzheimer degenerative disordersTau proteins: the molecular structure and mode of binding on microtubulesIdentification of septins in neurofibrillary tangles in Alzheimer's diseaseUp-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's diseaseStepping closer to treating Alzheimer's disease patients with BACE1 inhibitor drugsNeurotrophic factor small-molecule mimetics mediated neuroregeneration and synaptic repair: emerging therapeutic modality for Alzheimer's diseaseNMR Meets Tau: Insights into Its Function and PathologyNew Features about Tau Function and DysfunctionTau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective StrategiesThe endocrine dyscrasia that accompanies menopause and andropause induces aberrant cell cycle signaling that triggers re-entry of post-mitotic neurons into the cell cycle, neurodysfunction, neurodegeneration and cognitive diseaseHuman fetal tau protein isoform: possibilities for Alzheimer's disease treatmentWho fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathwaysPreclinical Alzheimer disease: identification of cases at risk among cognitively intact older individualsConnecting the dots between tau dysfunction and neurodegenerationAlzheimer's pathogenesis and its link to the mitochondrionEffect of the inhaled anesthetics isoflurane, sevoflurane and desflurane on the neuropathogenesis of Alzheimer's disease (review)Clinicopathologic assessment and imaging of tauopathies in neurodegenerative dementiasApolipoprotein A-I: insights from redox proteomics for its role in neurodegenerationDexmedetomidine increases tau phosphorylation under normothermic conditions in vivo and in vitro.Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease PhenotypesAn Ultra-specific Avian Antibody to Phosphorylated Tau Protein Reveals a Unique Mechanism for Phosphoepitope RecognitionThe Impact of Vitamin E and Other Fat-Soluble Vitamins on Alzheimer´s DiseaseTau StructuresStructural MR Imaging in the Diagnosis of Alzheimer's Disease and Other Neurodegenerative Dementia: Current Imaging Approach and Future PerspectivesPropofol directly increases tau phosphorylationMemantine Attenuates Alzheimer's Disease-Like Pathology and Cognitive ImpairmentPreclinical Metabolism, Pharmacokinetics and In Vivo Analysis of New Blood-Brain-Barrier Penetrant Fingolimod Analogues: FTY720-C2 and FTY720-MitoxyMicrotubule bundling by tau proteins in vivo: analysis of functional domainsIsolation and chemical characterization of Alzheimer's disease paired helical filament cytoskeletons: differentiation from amyloid plaque core protein
P2860
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P2860
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh-hant
name
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.
@en
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.
@nl
type
label
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.
@en
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.
@nl
prefLabel
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.
@en
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.
@nl
P2093
P1476
Microtubule-associated protein tau. A component of Alzheimer paired helical filaments.
@en
P2093
Grundke-Iqbal I
Wisniewski HM
P304
P407
P577
1986-05-01T00:00:00Z