about
Generation of a Novel Bacteriophage Library Displaying scFv Antibody Fragments from the Natural Buffalo Host to Identify Antigens from Adult Schistosoma japonicum for Diagnostic DevelopmentEffective pulmonary delivery of an aerosolized plasmid DNA vaccine via surface acoustic wave nebulization.Development and application of a fecal antigen diagnostic sandwich ELISA for estimating prevalence of Fasciola gigantica in cattle in central Java, Indonesia.Immune cell kinetics in the ovine abomasal mucosa following hyperimmunization and challenge with Haemonchus contortusDiscovery of novel Schistosoma japonicum antigens using a targeted protein microarray approach.Resistance to liver fluke infection in the natural sheep host is correlated with a type-1 cytokine response.Current status for gastrointestinal nematode diagnosis in small ruminants: where are we and where are we going?The effect of plant tissue and vaccine formulation on the oral immunogenicity of a model plant-made antigen in sheep.Cloning and expression of the major secreted cathepsin B-like protein from juvenile Fasciola hepatica and analysis of immunogenicity following liver fluke infection.Local immune responses of the Chinese water buffalo, Bubalus bubalis, against Schistosoma japonicum larvae: crucial insights for vaccine design.The in vitro anthelmintic effects of plumbagin on newly excysted and 4-weeks-old juvenile parasites of Fasciola gigantica.The effect of different adjuvants on immune parameters and protection following vaccination of sheep with a larval-specific antigen of the gastrointestinal nematode, Haemonchus contortusExploiting natural immunity to helminth parasites for the development of veterinary vaccines.Using the local immune response from the natural buffalo host to generate an antibody fragment library that binds the early larval stages of Schistosoma japonicum.Dynamics of IL-4 and IL-13 expression in the airways of sheep following allergen challenge.Potential role for mucosal IgA in modulating Haemonchus contortus adult worm infection in sheep.Evaluation of the immune responses induced by four targeted DNA vaccines encoding the juvenile liver fluke antigen, cathepsin B in a mouse model.A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasitesImmune mechanisms of resistance to gastrointestinal nematode infections in sheep.Liver fluke vaccines in ruminants: strategies, progress and future opportunities.Immunity to Haemonchus contortus and Vaccine Development.Specific humoral response of hosts with variable schistosomiasis susceptibility.Low cost whole-organism screening of compounds for anthelmintic activity.A novel ex vivo immunoproteomic approach characterising Fasciola hepatica tegumental antigens identified using immune antibody from resistant sheep.Modulation of Haemonchus contortus infection by depletion of γδ+ T cells in parasite resistant Canaria Hair Breed sheep.Selection of multi-drug resistant influenza A and B viruses under zanamivir pressure and their replication fitness in ferrets.Cloning, expression, purification and crystallographic studies of galectin-11 from domestic sheep (Ovis aries)Galectin-11: A novel host mediator targeting specific stages of the gastrointestinal nematode parasite, Haemonchus contortus.Evaluation of a dry powder delivery system for laninamivir in a ferret model of influenza infection.Peritoneal lavage cells of Indonesian thin-tail sheep mediate antibody-dependent superoxide radical cytotoxicity in vitro against newly excysted juvenile Fasciola gigantica but not juvenile Fasciola hepaticaIncreased production through parasite control: can ancient breeds of sheep teach us new lessons?Molecular cloning and characterisation of ovine dual oxidase 2.The developing schistosome worms elicit distinct immune responses in different tissue regions.The relationship between the rapid rejection of Haemonchus contortus larvae with cells and mediators in abomasal tissues in immune sheep.Vaccination against fasciolosis by a multivalent vaccine of stage-specific antigens.Comparative experimental Haemonchus contortus infection of two sheep breeds native to the Canary Islands.Innate and adaptive resistance of Indonesian Thin Tail sheep to liver fluke: a comparative analysis of Fasciola gigantica and Fasciola hepatica infection.The kinetics of local cytokine and galectin expression after challenge infection with the gastrointestinal nematode, Haemonchus contortus.Proteomic identification of galectin-11 and 14 ligands from Haemonchus contortus.Dual oxidase 2 and glutathione peroxidase gene expression are elevated in hyperimmunized sheep challenged with Haemonchus contortus.
P50
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P50
description
hulumtues
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researcher
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wetenschapper
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հետազոտող
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name
David Piedrafita
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David Piedrafita
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David Piedrafita
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David Piedrafita
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David Piedrafita
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David Piedrafita
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David Piedrafita
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David Piedrafita
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David Piedrafita
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David Piedrafita
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David Piedrafita
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David Piedrafita
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David Piedrafita
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David Piedrafita
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David Piedrafita
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P106
P21
P31
P496
0000-0001-8692-990X