ARID1A-mutated ovarian cancers depend on HDAC6 activity. - Wikidata - wikimedia - TriplyDB

ARID1A-mutated ovarian cancers depend on HDAC6 activity.

ARID1A-mutated ovarian cancers depend on HDAC6 activity.

http://www.wikidata.org/entity/Q48358070

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A key HDAC6 dependency of ARID1A-mutated ovarian cancer.Ovarian Cancers: Genetic Abnormalities, Tumor Heterogeneity and Progression, Clonal Evolution and Cancer Stem Cells.Harnessing mutual exclusivity between TP53 and ARID1 A mutations.Association of histone deacetylase expression with histology and prognosis of ovarian cancer.CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity.Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer.Optimised ARID1A immunohistochemistry is an accurate predictor of ARID1A mutational status in gynaecological cancers.Integrative kinome profiling identifies mTORC1/2 inhibition as treatment strategy in ovarian clear cell carcinoma.Inhibition of HDAC6 activity in kidney diseases: a new perspective.SWI/SNF catalytic subunits' switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells Targeting AURKA-CDC25C axis to induce synthetic lethality in ARID1A-deficient colorectal cancer cells Silencing of HDAC6 as a therapeutic target in chronic lymphocytic leukemia

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ARID1A-mutated ovarian cancers depend on HDAC6 activity.

http://www.wikidata.org/entity/Q48358070

description

2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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name

ARID1A-mutated ovarian cancers depend on HDAC6 activity.

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ARID1A-mutated ovarian cancers depend on HDAC6 activity.

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type

label

ARID1A-mutated ovarian cancers depend on HDAC6 activity.

@en

ARID1A-mutated ovarian cancers depend on HDAC6 activity.

@nl

prefLabel

ARID1A-mutated ovarian cancers depend on HDAC6 activity.

@en

ARID1A-mutated ovarian cancers depend on HDAC6 activity.

@nl

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Nature Cell Biology

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ARID1A-mutated ovarian cancers depend on HDAC6 activity.

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Ana Vara-Ailor

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Andrew V Kossenkov

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David G Huntsman

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David W Christianson

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David W Speicher

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Frank J Rauscher

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Jose R Conejo-Garcia

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Katherine M Aird

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Pyoung Hwa Park

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Weiping Zou

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P2860

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

ARID1A mutations in endometriosis-associated ovarian carcinomas

Histone deacetylase 6 plays a role as a distinct regulator of diverse cellular processes

Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers

Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes

Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma

Discovery and saturation analysis of cancer genes across 21 tumour types

ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a

Identification of novel therapeutic targets in microdissected clear cell ovarian cancers

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

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962-973

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scholarly article

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10.1038/NCB3582

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8

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19

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Benjamin G Bitler

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2017-07-24T00:00:00Z

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28737768

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