Chlorinated adenosine analogue induces AMPK and autophagy in chronic lymphocytic leukaemia cells during therapy.

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Targeting the Adenosinergic Axis in Chronic Lymphocytic Leukemia: A Way to Disrupt the Tumor Niche?

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Chlorinated adenosine analogue induces AMPK and autophagy in chronic lymphocytic leukaemia cells during therapy.

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http://www.wikidata.org/entity/Q48359128

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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Chlorinated adenosine analogue ...... eukaemia cells during therapy.

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Chlorinated adenosine analogue ...... eukaemia cells during therapy.

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label

Chlorinated adenosine analogue ...... eukaemia cells during therapy.

@en

Chlorinated adenosine analogue ...... eukaemia cells during therapy.

@nl

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Chlorinated adenosine analogue ...... eukaemia cells during therapy.

@en

Chlorinated adenosine analogue ...... eukaemia cells during therapy.

@nl

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Chlorinated adenosine analogue ...... eukaemia cells during therapy.

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Christine M Stellrecht

http://www.w3.org/2001/XMLSchema#string

Jennifer B Dennison

http://www.w3.org/2001/XMLSchema#string

Lisa S Chen

http://www.w3.org/2001/XMLSchema#string

Mary L Ayres

http://www.w3.org/2001/XMLSchema#string

Shujun Shentu

http://www.w3.org/2001/XMLSchema#string

Varsha Gandhi

http://www.w3.org/2001/XMLSchema#string

Yuling Chen

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P2860

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy

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Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

ATP directed agent, 8-chloro-adenosine, induces AMP activated protein kinase activity, leading to autophagic cell death in breast cancer cells.

Cell death of bioenergetically compromised and transcriptionally challenged CLL lymphocytes by chlorinated ATP

Preclinical activity of 8-chloroadenosine with mantle cell lymphoma: roles of energy depletion and inhibition of DNA and RNA synthesis.

AMP-activated protein kinase: maintaining energy homeostasis at the cellular and whole-body levels.

A unique RNA-directed nucleoside analog is cytotoxic to breast cancer cells and depletes cyclin E levels.

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266-271

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scholarly article

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10.1111/BJH.14859

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English

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http://www.w3.org/2001/XMLSchema#string

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179

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William G Wierda

Michael J. Keating

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2017-07-24T00:00:00Z

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28737232

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leukemia

lymphocyte

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5638689

http://www.w3.org/2001/XMLSchema#string

Chlorinated adenosine analogue induces AMPK and autophagy in chronic lymphocytic leukaemia cells during therapy.

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P2860

P2860

Chlorinated adenosine analogue induces AMPK and autophagy in chronic lymphocytic leukaemia cells during therapy.

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type

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932