Targeted disruption of the gene encoding core 1 beta1-3-galactosyltransferase (T-synthase) causes embryonic lethality and defective angiogenesis in mice.
about
C1GALT1 overexpression promotes the invasive behavior of colon cancer cells through modifying O-glycosylation of FGFR2.COSMC is overexpressed in proliferating infantile hemangioma and enhances endothelial cell growth via VEGFR2.Aberrant Cosmc genes result in Tn antigen expression in human colorectal carcinoma cell line HT-29.Loss of intestinal O-glycans promotes spontaneous duodenal tumors.Short stop mediates axonal compartmentalization of mucin-type core 1 glycans.The Tn antigen-structural simplicity and biological complexity.Knockdown of core 1 beta 1, 3-galactosyltransferase prolongs skin allograft survival with induction of galectin-1 secretion and suppression of CD8+ T cells: T synthase knockdown effects on galectin-1 and CD8+ T cells.The molecular chaperone Cosmc enhances malignant behaviors of colon cancer cells via activation of Akt and ERK.Sialylation on O-glycans protects platelets from clearance by liver Kupffer cells.Glucuronylated core 1 glycans are required for precise localization of neuromuscular junctions and normal formation of basement membranes on Drosophila muscles.
P2860
Q33688535-9125D3CE-107C-49FB-9E99-5D22FDADDC46Q34592757-FD8E9E47-BC57-4930-8345-C94970439678Q35632101-11D55E1D-4445-4742-ABC7-DCAB76311D52Q37139510-5918DF14-F96A-4FBE-94A6-853792B5A243Q37620555-360F4317-A32A-4C4E-9F23-33FF67FA2AE0Q37831859-CDDB0978-897C-481D-B5E1-B4AC91650C17Q39385052-10F977AC-12DF-40B5-854B-73399DB36E6FQ44392892-FFC2B90F-8C44-4B9C-AEC3-B4130DC76DA5Q46215378-5B3D25C8-5B45-4205-8920-12C81E649546Q52369334-D7A47F63-ABE5-4357-AACD-BB6A7C354E64
P2860
Targeted disruption of the gene encoding core 1 beta1-3-galactosyltransferase (T-synthase) causes embryonic lethality and defective angiogenesis in mice.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Targeted disruption of the gen ...... efective angiogenesis in mice.
@en
Targeted disruption of the gene encoding core 1 beta1-3-galactosyltransferase
@nl
type
label
Targeted disruption of the gen ...... efective angiogenesis in mice.
@en
Targeted disruption of the gene encoding core 1 beta1-3-galactosyltransferase
@nl
prefLabel
Targeted disruption of the gen ...... efective angiogenesis in mice.
@en
Targeted disruption of the gene encoding core 1 beta1-3-galactosyltransferase
@nl
P1476
Targeted disruption of the gen ...... efective angiogenesis in mice.
@en
P2093
Rodger P McEver
P304
P356
10.1016/S0076-6879(06)16021-8
P407
P577
2006-01-01T00:00:00Z