Human striatal L-dopa decarboxylase activity estimated in vivo using 6-[18F]fluoro-dopa and positron emission tomography: error analysis and application to normal subjects.
about
Cellular replacement therapy for Parkinson's disease--where we are today?Increase in dopamine turnover occurs early in Parkinson's disease: evidence from a new modeling approach to PET 18 F-fluorodopa data.The sensitivity of 18-fluorodopa positron emission tomography and magnetic resonance imaging in Parkinson's disease.Increased turnover of dopamine in caudate nucleus of detoxified alcoholic patientsImaging end points for monitoring neuroprotection in Parkinson's disease.Role of dopamine transporter imaging in investigation of parkinsonian syndromes in routine clinical practice.Elevated dopa decarboxylase activity in living brain of patients with psychosis.Fluorodopa positron emission tomography with an inhibitor of catechol-O-methyltransferase: effect of the plasma 3-O-methyldopa fraction on data analysis.Synthesis and biological evaluation of novel carbon-11 labeled pyridyl ethers: candidate ligands for in vivo imaging of alpha4beta2 nicotinic acetylcholine receptors (alpha4beta2-nAChRs) in the brain with positron emission tomographyPlasma radiometabolite correction in dynamic PET studies: Insights on the available modeling approaches.Aromatic L-amino acid decarboxylase: a neglected and misunderstood enzyme.Compartmental analysis of dopa decarboxylation in living brain from dynamic positron emission tomograms.Striatal kinetic modeling of FDOPA with a cerebellar-derived constraint on the distribution of volume of 30MFD: a PET investigation using non-human primates.A reversible tracer analysis approach to the study of effective dopamine turnover.Loss of metabolites from monkey striatum during PET with FDOPA.Blinded positron emission tomography study of dopamine cell implantation for Parkinson's disease.Sensitivity of kinetic macro parameters to changes in dopamine synthesis, storage, and metabolism: a simulation study for [¹⁸F]FDOPA PET by a model with detailed dopamine pathway.Effect of dopamine loss and the metabolite 3-O-methyl-[18F]fluoro-dopa on the relation between the 18F-fluorodopa tissue input uptake rate constant Kocc and the [18F]fluorodopa plasma input uptake rate constant Ki.Restorative Strategies in Movement Disorders: the Contribution of Imaging.Dopamine storage capacity in caudate and putamen of patients with early Parkinson's disease: correlation with asymmetry of motor symptoms.11 C-PE2I and 18 F-Dopa PET for assessing progression rate in Parkinson's: A longitudinal study.The distribution and kinetics of [18F]6-fluoro-3-O-methyl-L-dopa in the human brain.Brain uptake of alpha-[14C]methyl-para-tyrosine in the rat.Cerebral 6-[(18)F]fluoro-L-DOPA (FDOPA) metabolism in pig studied by positron emission tomography.Pharmacokinetics of plasma 6-[18F]fluoro-L-3,4-dihydroxyphenylalanine ([18F]Fdopa) in humans.Comparison between the decrease of dopamine transporter and that of L-DOPA uptake for detection of early to advanced stage of Parkinson's disease in animal models.Effect of catechol-O-methyltransferase inhibition on brain uptake of [18F]fluorodopa: implications for compartmental modelling and clinical usefulness.6-[18F]fluoro-L-dopa metabolism in living human brain: a comparison of six analytical methods.Validation of the three-dimensional acquisition mode in positron emission tomography for the quantitation of [18F]fluoro-DOPA uptake in the human striata.On the rate of decarboxylation of dopa to dopamine in living mammalian brain.Striatal 6-[18F]fluorodopa accumulation after combined inhibition of peripheral catechol-O-methyltransferase and monoamine oxidase type B: differing response in relation to presynaptic dopaminergic dysfunction.A comparison of 11C-labeled L-DOPA and L-fluorodopa as positron emission tomography tracers for the presynaptic dopaminergic system.Positron emission tomographic imaging of the dopamine transporter with 11C-WIN 35,428 reveals marked declines in mild Parkinson's disease.DOPA Decarboxylase
P2860
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P2860
Human striatal L-dopa decarboxylase activity estimated in vivo using 6-[18F]fluoro-dopa and positron emission tomography: error analysis and application to normal subjects.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh-hant
name
Human striatal L-dopa decarbox ...... pplication to normal subjects.
@en
Human striatal L-dopa decarbox ...... pplication to normal subjects.
@nl
type
label
Human striatal L-dopa decarbox ...... pplication to normal subjects.
@en
Human striatal L-dopa decarbox ...... pplication to normal subjects.
@nl
prefLabel
Human striatal L-dopa decarbox ...... pplication to normal subjects.
@en
Human striatal L-dopa decarbox ...... pplication to normal subjects.
@nl
P2093
P2860
P356
P1476
Human striatal L-dopa decarbox ...... pplication to normal subjects.
@en
P2093
P2860
P356
10.1038/JCBFM.1993.7
P577
1993-01-01T00:00:00Z