Fingolimod (FTY720) inhibits neuroinflammation and attenuates spontaneous convulsions in lithium-pilocarpine induced status epilepticus in rat model.
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Fingolimod for the treatment of neurological diseases-state of play and future perspectivesPreclinical Metabolism, Pharmacokinetics and In Vivo Analysis of New Blood-Brain-Barrier Penetrant Fingolimod Analogues: FTY720-C2 and FTY720-MitoxyThe potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments.Fingolimod Limits Acute Aβ Neurotoxicity and Promotes Synaptic Versus Extrasynaptic NMDA Receptor Functionality in Hippocampal NeuronsAnticonvulsant effects of antiaris toxicaria aqueous extract: investigation using animal models of temporal lobe epilepsyNovel FTY720-Based Compounds Stimulate Neurotrophin Expression and Phosphatase Activity in Dopaminergic Cells.Neuropeptide Y protects cerebral cortical neurons by regulating microglial immune functionImmunity and inflammation in status epilepticus and its sequelae: possibilities for therapeutic application.Past and present definitions of epileptogenesis and its biomarkers.Treatment of status epilepticus with ketamine, are we there yet?Fingolimod Exerts only Temporary Antiepileptogenic Effects but Longer-Lasting Positive Effects on Behavior in the WAG/Rij Rat Absence Epilepsy Model.Fingolimod exerts neuroprotective effects in a mouse model of intracerebral hemorrhageIdentification of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P1) as a Pathogenic Factor in Transient Focal Cerebral Ischemia.Therapeutic Strategies Under Development Targeting Inflammatory Mechanisms in Amyotrophic Lateral Sclerosis.Modulators of microglial activation and polarization after intracerebral haemorrhage.FTY720 attenuates excitotoxicity and neuroinflammation.Effects of FTY720 on brain neurogenic niches in vitro and after kainic acid-induced injuryClinical studies and anti-inflammatory mechanisms of treatments.α-Asarone Attenuates Cognitive Deficit in a Pilocarpine-Induced Status Epilepticus Rat Model via a Decrease in the Nuclear Factor-κB Activation and Reduction in Microglia Neuroinflammation.Fingolimod affects gene expression profile associated with LPS-induced memory impairment.Chronic Trigeminal Nerve Stimulation Protects Against Seizures, Cognitive Impairments, Hippocampal Apoptosis, and Inflammatory Responses in Epileptic Rats.TNFα disrupts blood brain barrier integrity to maintain prolonged depressive-like behavior in mice.
P2860
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P2860
Fingolimod (FTY720) inhibits neuroinflammation and attenuates spontaneous convulsions in lithium-pilocarpine induced status epilepticus in rat model.
description
2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
@zh-hans
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@zh-my
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name
Fingolimod (FTY720) inhibits n ...... atus epilepticus in rat model.
@en
type
label
Fingolimod (FTY720) inhibits n ...... atus epilepticus in rat model.
@en
prefLabel
Fingolimod (FTY720) inhibits n ...... atus epilepticus in rat model.
@en
P2093
P1476
Fingolimod (FTY720) inhibits n ...... atus epilepticus in rat model.
@en
P2093
P304
P356
10.1016/J.PBB.2012.08.025
P407
P577
2012-08-31T00:00:00Z