Quantitative analysis of O6-alkylguanine-DNA alkyltransferase in malignant glioma.
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O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patientsO(6)-methylguanine-DNA methyltransferase in glioma therapy: promise and problemsBevacizumab and daily temozolomide for recurrent glioblastoma.Mismatch repair deficiency does not mediate clinical resistance to temozolomide in malignant gliomaComprehensive analysis of MGMT promoter methylation: correlation with MGMT expression and clinical response in GBMO6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction.Usefulness of MS-MLPA for detection of MGMT promoter methylation in the evaluation of pseudoprogression in glioblastoma patients.Molecular pathology in adult gliomas: diagnostic, prognostic, and predictive markersO6-methylguanine DNA methyltransferase deficiency and response to temozolomide-based therapy in patients with neuroendocrine tumors.MGMT testing allows for personalised therapy in the temozolomide era.MGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCRA phase II study of O6-benzylguanine and temozolomide in pediatric patients with recurrent or progressive high-grade gliomas and brainstem gliomas: a Pediatric Brain Tumor Consortium study.Decoupling of DNA damage response signaling from DNA damages underlies temozolomide resistance in glioblastoma cells.Molecular diagnostic testing in malignant gliomas: a practical update on predictive markers.Expression of O(6)-Methylguanine-DNA Methyltransferase Examined by Alkyl-Transfer Assays, Methylation-Specific PCR and Western Blots in Tumors and Matched Normal Tissue.Extent of MGMT promoter methylation correlates with outcome in glioblastomas given temozolomide and radiotherapyIdentification of regions correlating MGMT promoter methylation and gene expression in glioblastomas.Correlation of histomorphologic prognostic markers and proliferative index with loss of heterozygosity 1p/19q and MGMT status in diffusely infiltrating gliomas.MGMT testing for glioma in clinical laboratories: discordance with methylation analyses prevents the implementation of routine immunohistochemistry.Identification of MGMT promoter methylation sites correlating with gene expression and IDH1 mutation in gliomas.Cell type specificity of signaling: view from membrane receptors distribution and their downstream transduction networks.Correlation between quantified promoter methylation and enzymatic activity of O6-methylguanine-DNA methyltransferase in glioblastomas."MGMT for pt mgmt": is methylguanine-DNA methyltransferase testing ready for patient management?O6-methylguanine DNA methyltransferase expression in tumor cells predicts outcome of radiotherapy plus concomitant and adjuvant temozolomide therapy in patients with primary glioblastoma.Quantitative digital assessment of MGMT immunohistochemical expression in glioblastoma tissue.O(6)-methylguanine-DNA methyltransferase activity is associated with response to alkylating agent therapy and with MGMT promoter methylation in glioblastoma and anaplastic glioma.MGMT in primary and recurrent human glioblastomas after radiation and chemotherapy and comparison with p53 status and clinical outcome.Expression of O⁶-methylguanine DNA methyltransferase (MGMT) and immunohistochemical analysis of 12 pineal parenchymal tumors.Tumour and serum MGMT promoter methylation and protein expression in glioblastoma patients.Concordant association validates MGMT methylation and protein expression as favorable prognostic factors in glioma patients on alkylating chemotherapy (Temozolomide).
P2860
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P2860
Quantitative analysis of O6-alkylguanine-DNA alkyltransferase in malignant glioma.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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name
Quantitative analysis of O6-alkylguanine-DNA alkyltransferase in malignant glioma.
@en
Quantitative analysis of O6-alkylguanine-DNA alkyltransferase in malignant glioma.
@nl
type
label
Quantitative analysis of O6-alkylguanine-DNA alkyltransferase in malignant glioma.
@en
Quantitative analysis of O6-alkylguanine-DNA alkyltransferase in malignant glioma.
@nl
prefLabel
Quantitative analysis of O6-alkylguanine-DNA alkyltransferase in malignant glioma.
@en
Quantitative analysis of O6-alkylguanine-DNA alkyltransferase in malignant glioma.
@nl
P2093
P50
P1476
Quantitative analysis of O6-alkylguanine-DNA alkyltransferase in malignant glioma.
@en
P2093
Francis Ali-Osman
James E Herndon
Jennifer A Quinn
Jill A Maxwell
Joseph Bigley
Katja Bierau
Stewart P Johnson
P304
P356
10.1158/1535-7163.MCT-06-0106
P577
2006-10-01T00:00:00Z