N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth.
about
Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastomaCerebellum development and medulloblastomaCoordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19ARF-p53 pathwayN-Myc and L-Myc are essential for hair cell formation but not maintenanceMusashi1 modulates cell proliferation genes in the medulloblastoma cell line DaoyN-Myc regulates expression of pluripotency genes in neuroblastoma including lif, klf2, klf4, and lin28b.Stress-induced cleavage of Myc promotes cancer cell survivalControlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental SignalingPrimary brain tumors, neural stem cell, and brain tumor cancer cells: where is the link?Dexamethasone destabilizes Nmyc to inhibit the growth of hedgehog-associated medulloblastomaHedgehog pathway-regulated gene networks in cerebellum development and tumorigenesis.c-myc and N-myc promote active stem cell metabolism and cycling as architects of the developing brain.Reprogramming fibroblasts into induced pluripotent stem cells with Bmi1.Sonic hedgehog signaling in the postnatal brain.Role of the miR-17∼92 cluster family in cerebellar and medulloblastoma development.Widespread contribution of Gdf7 lineage to cerebellar cell types and implications for hedgehog-driven medulloblastoma formation.N-Myc and GCN5 regulate significantly overlapping transcriptional programs in neural stem cells.c- and N-myc regulate neural precursor cell fate, cell cycle, and metabolism to direct cerebellar development.Deregulated proliferation and differentiation in brain tumors.Myc on my mind: a transcription factor family's essential role in brain developmentMolecular and in vivo characterization of cancer-propagating cells derived from MYCN-dependent medulloblastomaAnalysis of hedgehog signaling in cerebellar granule cell precursors in a conditional Nsdhl allele demonstrates an essential role for cholesterol in postnatal CNS development.MycN Is Critical for the Maintenance of Human Embryonic Stem Cell-Derived Neural Crest Stem CellsMyc proteins in brain tumor development and maintenance.Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.The deubiquitylase USP37 links REST to the control of p27 stability and cell proliferationN-myc coordinates retinal growth with eye size during mouse development.MicroRNA-17-92 cluster mediates the proliferation and survival of neural progenitor cells after stroke.Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency.MicroRNAs in cerebral ischemia-induced neurogenesis.Dynamic signaling for neural stem cell fate determination.Medulloblastoma stem cells.Neuroblastoma and MYCNBMPs oppose Math1 in cerebellar development and in medulloblastoma.Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas.Molecular diagnostics of CNS embryonal tumors.Role of nitric oxide in cerebellar development and function: focus on granule neurons.The clinical implications of medulloblastoma subgroups.INSM1 increases N-myc stability and oncogenesis via a positive-feedback loop in neuroblastomaIntegrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma.
P2860
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P2860
N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
N-myc is an essential downstre ...... neoplastic cerebellar growth.
@en
N-myc is an essential downstre ...... neoplastic cerebellar growth.
@nl
type
label
N-myc is an essential downstre ...... neoplastic cerebellar growth.
@en
N-myc is an essential downstre ...... neoplastic cerebellar growth.
@nl
prefLabel
N-myc is an essential downstre ...... neoplastic cerebellar growth.
@en
N-myc is an essential downstre ...... neoplastic cerebellar growth.
@nl
P2093
P1433
P1476
N-myc is an essential downstre ...... d neoplastic cerebellar growth
@en
P2093
Anna Marie Kenney
Beryl A Hatton
Ignacio Moreno de Alborán
James M Olson
Robert N Eisenman
P304
P356
10.1158/0008-5472.CAN-06-1621
P407
P577
2006-09-01T00:00:00Z