Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas. - Wikidata - wikimedia - TriplyDB

Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.

Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.

http://www.wikidata.org/entity/Q48448124

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Prognostic value of increased KPNA2 expression in some solid tumors: A systematic review and meta-analysis Karyopherin alpha 2 expression is a novel diagnostic and prognostic factor for colorectal cancer Glioblastoma development in mouse brain: general reduction of OCTs and mislocalization of OCT3 transporter and subsequent uptake of ASP(+) substrate to the nuclei Molecular profiling of multiple human cancers defines an inflammatory cancer-associated molecular pattern and uncovers KPNA2 as a uniform poor prognostic cancer marker Diversification of importin-α isoforms in cellular trafficking and disease states Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.Karyopherin Alpha Proteins Regulate Oligodendrocyte Differentiation.MiR-26b/KPNA2 axis inhibits epithelial ovarian carcinoma proliferation and metastasis through downregulating OCT4.Low cytoplasmic and nuclear KPNA2 expression in radiotherapy-treated head and neck squamous cell cancer is associated with an adverse outcome.KPNA2 promotes cell proliferation and tumorigenicity in epithelial ovarian carcinoma through upregulation of c-Myc and downregulation of FOXO3a.mTOR regulates proteasomal degradation and Dp1/E2F1- mediated transcription of KPNA2 in lung cancer cells Downregulation of KPNA2 in non-small-cell lung cancer is associated with Oct4 expression An intrinsic DFF40/CAD endonuclease deficiency impairs oligonucleosomal DNA hydrolysis during caspase-dependent cell death: a common trait in human glioblastoma cells.Silencing of karyopherin α2 inhibits cell growth and survival in human hepatocellular carcinoma Elevated preoperative neutrophil/lymphocyte ratio is associated with poor prognosis in soft-tissue sarcoma patients.High nuclear karyopherin α 2 expression is a strong and independent predictor of biochemical recurrence in prostate cancer patients treated by radical prostatectomy.KPNA2 promotes migration and invasion in epithelial ovarian cancer cells by inducing epithelial-mesenchymal transition via Akt/GSK-3β/Snail activation.Karyopherin α-2 is a reliable marker for identification of patients with high-risk stage II colorectal cancer.Astrocytic exportin-7 responds to ischemia through mediating LKB1 translocation from the nucleus to the cytoplasm.KPNA2 is a potential diagnostic serum biomarker for epithelial ovarian cancer and correlates with poor prognosis.High expression of karyopherin-α2 and stathmin 1 is associated with proliferation potency and transformation in the bile duct and gall bladder epithelia in the cases of pancreaticobiliary maljunction.Upregulated Expression of Karyopherin α2 is Involved in Neuronal Apoptosis Following Intracerebral Hemorrhage in Adult Rats.Silencing of the nucleocytoplasmic shuttling protein karyopherin a2 promotes cell-cycle arrest and apoptosis in glioblastoma multiforme

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Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.

http://www.wikidata.org/entity/Q48448124

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

@zh-cn

2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh-hant

name

Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.

@en

Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.

@nl

type

label

Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.

@en

Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.

@nl

prefLabel

Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.

@en

Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.

@nl

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S11060-012-0924-2

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Journal of Neuro-Oncology

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Nuclear karyopherin a2: a novel biomarker for infiltrative astrocytomas.

@en

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A J Becker

http://www.w3.org/2001/XMLSchema#string

K Gousias

http://www.w3.org/2001/XMLSchema#string

M Simon

http://www.w3.org/2001/XMLSchema#string

P Niehusmann

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P2860

IDH1 and IDH2 mutations in gliomas

MGMT gene silencing and benefit from temozolomide in glioblastoma.

Importin KPNA2, NBS1, DNA repair and tumorigenesis

Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt

Gene Expression Profiling of Primary Cutaneous Melanoma and Clinical Outcome

Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis

Molecular profiling of laser-microdissected matched tumor and normal breast tissue identifies karyopherin alpha2 as a potential novel prognostic marker in breast cancer.

Karyopherin-alpha2 protein interacts with Chk2 and contributes to its nuclear import.

Truncated form of importin alpha identified in breast cancer cell inhibits nuclear import of p53.

Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas.

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s11060-012-0924-2

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545-553

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10.1007/S11060-012-0924-2

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3

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