Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization.
about
Spinal muscular atrophyAbsence of gemin5 from SMN complexes in nuclear Cajal bodiesThe survival motor neuron protein forms soluble glycine zipper oligomersIndoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanismA SMN missense mutation complements SMN2 restoring snRNPs and rescuing SMA miceTracking the Fragile X Mental Retardation Protein in a Highly Ordered Neuronal RiboNucleoParticles Population: A Link between Stalled Polyribosomes and RNA GranulesThe spinal muscular atrophy disease protein SMN is linked to the Golgi networkSubcutaneous administration of TC007 reduces disease severity in an animal model of SMACompartmentalized Platforms for Neuro-Pharmacological ResearchGemin5 Binds to the Survival Motor Neuron mRNA to Regulate SMN ExpressionGenome-wide expression analysis of a spinal muscular atrophy model: towards discovery of new drug targetsThe survival of motor neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of poly(A) mRNA in primary motor neuron axons.Staufen recruitment into stress granules does not affect early mRNA transport in oligodendrocytesSmn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneuronsRNA and diseaseTranslational readthrough by the aminoglycoside geneticin (G418) modulates SMN stability in vitro and improves motor function in SMA mice in vivoHigh-efficiency transfection of cultured primary motor neurons to study protein localization, trafficking, and function.The COPI vesicle complex binds and moves with survival motor neuron within axons.The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.Ribonucleoprotein assembly defects correlate with spinal muscular atrophy severity and preferentially affect a subset of spliceosomal snRNPsSpinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?Proteomic assessment of a cell model of spinal muscular atrophyThe Survival of Motor Neuron Protein Acts as a Molecular Chaperone for mRNP AssemblySMN requirement for synaptic vesicle, active zone and microtubule postnatal organization in motor nerve terminalsAssays for the identification and prioritization of drug candidates for spinal muscular atrophyRNA exodus to Israel: RNA controlling function in the far reaches of the neuron. Workshop on RNA control on neuronal function.Subcellular transcriptome alterations in a cell culture model of spinal muscular atrophy point to widespread defects in axonal growth and presynaptic differentiation.Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3).Spinal Muscular Atrophy Therapeutics: Where do we Stand?Depletion of SMN by RNA interference in HeLa cells induces defects in Cajal body formation.The role of CELF proteins in neurological disorders.Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits.Deletion of murine Smn exon 7 directed to liver leads to severe defect of liver development associated with iron overload.The Genetics of Spinal Muscular Atrophy: Progress and Challenges.Dysfunction of axonal membrane conductances in adolescents and young adults with spinal muscular atrophyKnockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding.Axonal-SMN (a-SMN), a protein isoform of the survival motor neuron gene, is specifically involved in axonogenesis.Spinal muscular atrophy: the role of SMN in axonal mRNA regulation.Neurogenic and myogenic contributions to hereditary motor neuron disease.Therapy development for spinal muscular atrophy in SMN independent targets.
P2860
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P2860
Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Active transport of the surviv ...... 7 in cytoplasmic localization.
@en
Active transport of the surviv ...... 7 in cytoplasmic localization.
@nl
type
label
Active transport of the surviv ...... 7 in cytoplasmic localization.
@en
Active transport of the surviv ...... 7 in cytoplasmic localization.
@nl
prefLabel
Active transport of the surviv ...... 7 in cytoplasmic localization.
@en
Active transport of the surviv ...... 7 in cytoplasmic localization.
@nl
P2093
P1476
Active transport of the surviv ...... -7 in cytoplasmic localization
@en
P2093
Daewha Hong
Gary J Bassell
Honglai L Zhang
Robert H Singer
Shailesh M Shenoy
P304
P356
10.1523/JNEUROSCI.23-16-06627.2003
P407
P577
2003-07-01T00:00:00Z