MeCP2-dependent transcriptional repression regulates excitatory neurotransmission.
about
Emerging pharmacotherapies for neurodevelopmental disordersEpigenetics in the mature mammalian brain: effects on behavior and synaptic transmissionSignaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous systemDevelopmental Dynamics of Rett SyndromeExcitatory/Inhibitory Balance and Circuit Homeostasis in Autism Spectrum DisordersThe impact of MeCP2 loss- or gain-of-function on synaptic plasticityChannelopathy pathogenesis in autism spectrum disordersTranscriptional co-repressors and memory storageRett syndrome - biological pathways leading from MECP2 to disorder phenotypesMeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse numberIn vivo analysis of MEF2 transcription factors in synapse regulation and neuronal survivalEnhanced cell death in MeCP2 null cerebellar granule neurons exposed to excitotoxicity and hypoxiaMetabolic fingerprints of altered brain growth, osmoregulation and neurotransmission in a Rett syndrome modelMecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neuronsEnhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndromeMeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212.Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutationsA critical and cell-autonomous role for MeCP2 in synaptic scaling upBrain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturationStructure of FBP11 WW1-PL ligand complex reveals the mechanism of proline-rich ligand recognition by group II/III WW domains.Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function.Modeling psychiatric disorders at the cellular and network levelsNetwork hyperexcitability in hippocampal slices from Mecp2 mutant mice revealed by voltage-sensitive dye imaging.Preclinical research in Rett syndrome: setting the foundation for translational success.MeCP2 and histone deacetylases 1 and 2 in dorsal striatum collectively suppress repetitive behaviorsSynaptic circuit abnormalities of motor-frontal layer 2/3 pyramidal neurons in an RNA interference model of methyl-CpG-binding protein 2 deficiency.Unconventional transcriptional response to environmental enrichment in a mouse model of Rett syndrome.MeCP2 functions largely cell-autonomously, but also non-cell-autonomously, in neuronal maturation and dendritic arborization of cortical pyramidal neurons.GABAA receptor antagonism ameliorates behavioral and synaptic impairments associated with MeCP2 overexpressionMeCP2 is required for normal development of GABAergic circuits in the thalamus.Chronic lithium treatment elicits its antimanic effects via BDNF-TrkB dependent synaptic downscalingHistone deacetylases 1 and 2 form a developmental switch that controls excitatory synapse maturation and function.DNA modifications in the mammalian brainMeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulantsNeuronal activity-regulated gene transcription in synapse development and cognitive function.Cell-autonomous alterations in dendritic arbor morphology and connectivity induced by overexpression of MeCP2 in Xenopus central neurons in vivoA mouse model for MeCP2 duplication syndrome: MeCP2 overexpression impairs learning and memory and synaptic transmissionRett syndrome and the impact of MeCP2 associated transcriptional mechanisms on neurotransmissionMeCP2-mediated transcription repression in the basolateral amygdala may underlie heightened anxiety in a mouse model of Rett syndromeExperimental models of Rett syndrome based on Mecp2 dysfunction.
P2860
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P2860
MeCP2-dependent transcriptional repression regulates excitatory neurotransmission.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
MeCP2-dependent transcriptional repression regulates excitatory neurotransmission.
@en
MeCP2-dependent transcriptional repression regulates excitatory neurotransmission.
@nl
type
label
MeCP2-dependent transcriptional repression regulates excitatory neurotransmission.
@en
MeCP2-dependent transcriptional repression regulates excitatory neurotransmission.
@nl
prefLabel
MeCP2-dependent transcriptional repression regulates excitatory neurotransmission.
@en
MeCP2-dependent transcriptional repression regulates excitatory neurotransmission.
@nl
P1433
P1476
MeCP2-dependent transcriptional repression regulates excitatory neurotransmission.
@en
P2093
Erika D Nelson
P304
P356
10.1016/J.CUB.2006.02.062
P407
P577
2006-04-01T00:00:00Z