t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes.
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Breaking boundaries-coagulation and fibrinolysis at the neurovascular interfaceRecombinant Tissue Plasminogen Activator Induces Neurological Side Effects Independent on Thrombolysis in Mechanical Animal Models of Focal Cerebral Infarction: A Systematic Review and Meta-AnalysisSelective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin.Plasmin-dependent modulation of the blood-brain barrier: a major consideration during tPA-induced thrombolysis?Dendritic Cell-Mediated Phagocytosis but Not Immune Activation Is Enhanced by PlasminDesmoteplase for Acute Ischemic Stroke within 3 to 9 Hours after Symptom Onset: Evidence from Randomized Controlled TrialsEnhancing Anticancer Effect of Gefitinib across the Blood-Brain Barrier Model Using Liposomes Modified with One α-Helical Cell-Penetrating Peptide or Glutathione and Tween 80.Matrix metalloproteinases and blood-brain barrier disruption in acute ischemic stroke.Neurovascular unit in chronic pain.Adult human dental pulp stem cells promote blood-brain barrier permeability through vascular endothelial growth factor-a expression.LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.Astrocytes regulate the balance between plasminogen activation and plasmin clearance via cell-surface actin.Improved method for the preparation of a human cell-based, contact model of the blood-brain barrier.Desmoteplase as a potential treatment for cerebral ischaemia.Recombinant tissue-type plasminogen activator transiently enhances blood-brain barrier permeability during cerebral ischemia through vascular endothelial growth factor-mediated endothelial endocytosis in miceNovel Thrombolytics for Acute Ischemic Stroke: Challenges and Opportunities.tPA Modulation of the Blood-Brain Barrier: A Unifying Explanation for the Pleiotropic Effects of tPA in the CNS.Activities of wild-type and variant tissue-type plasminogen activators retained on vascular endothelial cells.Novel Thrombolytic Drug Based on Thrombin Cleavable Microplasminogen Coupled to a Single-Chain Antibody Specific for Activated GPIIb/IIIa.Physiologic variations in blood plasminogen levels affect outcomes after acute cerebral thromboembolism in mice: a pathophysiologic role for microvascular thrombosis.Editorial: The Role of the Plasminogen Activating System in Neurobiology.Plasmin Activation of Glial Cells through Protease-Activated Receptor 1.Modifying expression of EphA4 and its downstream targets improves functional recovery after stroke.Clinical significance of post-interventional cerebral hyperdensities after endovascular mechanical thrombectomy in acute ischaemic stroke.LDL receptor blockade reduces mortality in a mouse model of ischaemic stroke without improving tissue-type plasminogen activator-induced brain haemorrhage: towards pre-clinical simulation of symptomatic ICH.ADAM9 promotes lung cancer progression through vascular remodeling by VEGFA, ANGPT2, and PLAT.Fibrinolysis: from blood to the brain.Plasminogen-stimulated inflammatory cytokine production by airway smooth muscle cells is regulated by annexin A2.Postinterventional subarachnoid haemorrhage after endovascular stroke treatment with stent retrievers.
P2860
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P2860
t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
t-PA-specific modulation of a ...... kinase pathway in astrocytes.
@en
t-PA-specific modulation of a ...... kinase pathway in astrocytes.
@nl
type
label
t-PA-specific modulation of a ...... kinase pathway in astrocytes.
@en
t-PA-specific modulation of a ...... kinase pathway in astrocytes.
@nl
prefLabel
t-PA-specific modulation of a ...... kinase pathway in astrocytes.
@en
t-PA-specific modulation of a ...... kinase pathway in astrocytes.
@nl
P50
P1433
P1476
t-PA-specific modulation of a ...... o kinase pathway in astrocytes
@en
P2093
Robert L Medcalf
Roxann Freeman
P304
P356
10.1182/BLOOD-2011-07-369512
P407
P577
2012-01-19T00:00:00Z