HIV-1 Tat protein increases the permeability of brain endothelial cells by both inhibiting occludin expression and cleaving occludin via matrix metalloproteinase-9.
about
Interaction between Tat and Drugs of Abuse during HIV-1 Infection and Central Nervous System DiseaseThe cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disordersRoles and functions of HIV-1 Tat protein in the CNS: an overviewECM remodelling in IBD: innocent bystander or partner in crime? The emerging role of extracellular molecular events in sustaining intestinal inflammationOxidative Stress during HIV Infection: Mechanisms and ConsequencesDifferential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood-brain barrier dysfunctionSpecific increase in MDR1 mediated drug-efflux in human brain endothelial cells following co-exposure to HIV-1 and saquinavirHIV-1 Tat-mediated apoptosis in human blood-retinal barrier-associated cells.The Role of Caveolin 1 in HIV Infection and Pathogenesis.Tat 101-mediated enhancement of brain pericyte migration involves platelet-derived growth factor subunit B homodimer: implications for human immunodeficiency virus-associated neurocognitive disorders.Chronic central nervous system expression of HIV-1 Tat leads to accelerated rarefaction of neocortical capillaries and loss of red blood cell velocity heterogeneity.Matrix metalloproteinase-9 leads to claudin-5 degradation via the NF-κB pathway in BALB/c mice with eosinophilic meningoencephalitis caused by Angiostrongylus cantonensis.HIV-1 Tat activates a RhoA signaling pathway to reduce NMDA-evoked calcium responses in hippocampal neurons via an actin-dependent mechanismMonocytes mediate HIV neuropathogenesis: mechanisms that contribute to HIV associated neurocognitive disordersExercise modulates redox-sensitive small GTPase activity in the brain microvasculature in a model of brain metastasis formationEffect of human immunodeficiency virus on blood-brain barrier integrity and function: an update.Chronic morphine and HIV-1 Tat promote differential central nervous system trafficking of CD3+ and Ly6C+ immune cells in a murine Streptococcus pneumoniae infection model.Viral disruption of the blood-brain barrier.Matrix metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitisPeptide derived from HIV-1 TAT protein destabilizes a monolayer of endothelial cells in an in vitro model of the blood-brain barrier and allows permeation of high molecular weight proteinsJapanese encephalitis virus disrupts cell-cell junctions and affects the epithelial permeability barrier functionsMycoplasma genitalium promotes epithelial crossing and peripheral blood mononuclear cell infection by HIV-1HIV-1 Tat Regulates Occludin and Aβ Transfer Receptor Expression in Brain Endothelial Cells via Rho/ROCK Signaling PathwayMatrix metalloproteinase levels in early HIV infection and relation to in vivo brain status.RhoGTPases, actomyosin signaling and regulation of the epithelial Apical Junctional Complex.Passage of Magnetic Tat-Conjugated Fe3O4@SiO2 Nanoparticles Across In Vitro Blood-Brain BarrierInfection of pericytes in vitro by Japanese encephalitis virus disrupts the integrity of the endothelial barrier.Mechanism of blood-retinal barrier breakdown induced by HIV-1 (Review).Ischemic neurons activate astrocytes to disrupt endothelial barrier via increasing VEGF expression.PPAR agonist-mediated protection against HIV Tat-induced cerebrovascular toxicity is enhanced in MMP-9-deficient mice.Tight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation.Rho'ing in and out of cells: viral interactions with Rho GTPase signalingViral and cellular factors underlying neuropathogenesis in HIV associated neurocognitive disorders (HAND)Neuropathogenesis of HIV: from initial neuroinvasion to HIV-associated neurocognitive disorder (HAND)Viral sensing at the blood-brain barrier: new roles for innate immunity at the CNS vasculature.An Overview of Human Immunodeficiency Virus Type 1-Associated Common Neurological Complications: Does Aging Pose a Challenge?HIV and viral protein effects on the blood brain barrier.Microvascular Function in Aging Among Women Living with HIV.Role of Rho/ROCK signaling in the interaction of melanoma cells with the blood-brain barrier.Tat is a multifunctional viral protein that modulates cellular gene expression and functions.
P2860
Q26770397-9B00F973-2523-46C4-B7F4-F374FD3A53AFQ26777952-7D829150-FCA4-469E-B44D-979FEB02ACC4Q26996314-3A2F642F-65EB-4866-BB34-27B81305C684Q27015979-78AD61AB-6898-4070-A727-E0AE334676CEQ28077167-9D47DDEB-CC1D-4A91-AFF7-A175CFE45EB5Q28236758-F80D5CA9-9A1E-4B05-A839-331BE8737005Q28534049-77DF655F-EA8C-4631-B968-155F7E5381A6Q31158768-AF2D64B6-4AE6-4CED-9014-9D90236893B0Q32183747-F3E8575C-BCA6-4500-86A5-FFE2261EF25CQ34091216-9F922452-1D31-4100-88E7-17E4BA470BAEQ34324750-27034A3D-AE24-4432-ABA5-178D2D1A6C96Q34625448-C7026477-8DBD-4CC6-ABC7-2783E16EF374Q35007551-124AFB2B-9259-4C2A-B023-BCE488ECED46Q35154529-798D53BF-56C8-44D5-BEE2-B5FC7D803CFFQ35164355-A741565A-C350-404B-8F27-D0579D4F409BQ35708840-CA1130D7-C4AF-4097-8122-64E32DC752EDQ35814647-A6A96E5E-72B3-4EF6-811C-6CE77FF18996Q36007851-A6138FA4-A2BE-4652-B7D4-A43AB134E073Q36382078-DB4DAB7B-A533-4321-A1D1-2C8C2A0FF8AAQ36492911-A7F9CF48-1FE6-4106-AD00-4521A0B480BAQ37042534-35E49A3B-7CE0-4B04-899B-AC728C8E849AQ37165406-FF95F6ED-44A3-4BA9-9B65-91E7A801E516Q37176830-4652C89F-A283-4154-86C8-CE3101656A53Q37283984-FAF3892B-7F70-4292-9768-00D03D8524F3Q37319461-74FD2959-9D95-4311-A387-AFDC7B852F48Q37324876-CC0D8E09-EF5B-4384-8BD6-93971BE4CF2FQ37547516-C9B746BA-787B-4CAC-AB8F-F65193670BBCQ37652087-38B9EAB5-DF62-4B9E-9041-C0012DD527C4Q37662754-17AAB806-EF76-4F00-BCBD-8A6E3BBA067EQ37695319-09D7E935-56E0-45F9-8824-F4CF30B7CD8FQ38058856-BE4197DF-EF32-408B-B254-0A0B46EC468BQ38201237-11D0C3D2-193D-48D6-8AB0-2F4C536FAEEDQ38217388-D998669D-4279-44E0-8935-0F676DBFF753Q38258410-E78A80D9-8A31-4EA0-A1FD-C5FD32D0E656Q38351324-1ED03E5D-86CC-4947-B554-503008E7B51DQ38628801-62468230-FBD8-4C75-BBCD-D22F7A0800CDQ38824376-10A4DEF9-7F13-45C3-AB21-C21127374A2CQ38973318-BA8F0E7F-26F0-448C-AEC6-EA40626DC942Q39073709-B34CF8B4-7088-4CD2-87F9-08A8FC5BD8A5Q39130522-B278342E-C0D3-4D19-B7BE-59F9C88A000E
P2860
HIV-1 Tat protein increases the permeability of brain endothelial cells by both inhibiting occludin expression and cleaving occludin via matrix metalloproteinase-9.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
HIV-1 Tat protein increases th ...... ia matrix metalloproteinase-9.
@en
HIV-1 Tat protein increases th ...... ia matrix metalloproteinase-9.
@nl
type
label
HIV-1 Tat protein increases th ...... ia matrix metalloproteinase-9.
@en
HIV-1 Tat protein increases th ...... ia matrix metalloproteinase-9.
@nl
prefLabel
HIV-1 Tat protein increases th ...... ia matrix metalloproteinase-9.
@en
HIV-1 Tat protein increases th ...... ia matrix metalloproteinase-9.
@nl
P2093
P1433
P1476
HIV-1 Tat protein increases th ...... via matrix metalloproteinase-9
@en
P2093
P356
10.1016/J.BRAINRES.2011.11.052
P407
P50
P577
2011-12-07T00:00:00Z