RhoA/ROCK pathway mediates p38 MAPK activation and morphological changes downstream of P2Y12/13 receptors in spinal microglia in neuropathic pain.
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Rho kinase as a target for cerebral vascular disordersSpinal inhibition of p38 MAP kinase reduces inflammatory and neuropathic pain in male but not female mice: Sex-dependent microglial signaling in the spinal cord.Activation of microglial P2Y12 receptor is required for outward potassium currents in response to neuronal injury.Activity-triggered tetrapartite neuron-glial interactions following peripheral injuryMicroglial P2 Purinergic Receptor and Immunomodulatory Gene Transcripts Vary By Region, Sex, and Age in the Healthy Mouse CNS.Microglial P2Y12 receptors regulate microglial activation and surveillance during neuropathic pain.Rho/ROCK acts downstream of lysophosphatidic acid receptor 1 in modulating P2X3 receptor-mediated bone cancer pain in rats.SCISSOR-Spinal Cord Injury Study on Small molecule-derived Rho inhibition: a clinical study protocol."Three Methods and Three Points" regulates p38 mitogen-activated protein kinase in the dorsal horn of the spinal cord in a rat model of sciatic nerve injuryRhoA/Rho kinase in spinal cord injury.Modulation of Microglial Activity by Rho-Kinase (ROCK) Inhibition as Therapeutic Strategy in Parkinson's Disease and Amyotrophic Lateral Sclerosis.Targeting glia for bone cancer pain.Signaling Pathways Controlling Microglia Chemotaxis.Activation of dorsal horn cannabinoid CB2 receptor suppresses the expression of P2Y12 and P2Y13 receptors in neuropathic pain rats.P2Y12 and P2Y13 receptors involved in ADPβs induced the release of IL-1β, IL-6 and TNF-α from cultured dorsal horn microglia.P2Y12 receptor upregulation in satellite glial cells is involved in neuropathic pain induced by HIV glycoprotein 120 and 2',3'-dideoxycytidine.Structure, Pharmacology and Roles in Physiology of the P2Y12 Receptor.An Update on P2Y13 Receptor Signalling and Function.Epigallocatechin-3-gallate treatment reduces thermal hyperalgesia after spinal cord injury by down-regulating RhoA expression in mice.Activation of spinal dorsal horn P2Y13 receptors can promote the expression of IL-1β and IL-6 in rats with diabetic neuropathic pain.Disruption of the Microglial ADP Receptor P2Y13 Enhances Adult Hippocampal Neurogenesis.FSD-C10 Shows Therapeutic Effects in Suppressing oxidized low-density lipoprotein (ox-LDL)-Induced Human Brain Microvascular Endothelial Cells Apoptosis via Rho-Associated Coiled-Coil Kinase (ROCK)/Mitogen-Activated Protein Kinase (MAPK) Signaling
P2860
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P2860
RhoA/ROCK pathway mediates p38 MAPK activation and morphological changes downstream of P2Y12/13 receptors in spinal microglia in neuropathic pain.
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
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name
RhoA/ROCK pathway mediates p38 ...... microglia in neuropathic pain.
@en
RhoA/ROCK pathway mediates p38 ...... microglia in neuropathic pain.
@nl
type
label
RhoA/ROCK pathway mediates p38 ...... microglia in neuropathic pain.
@en
RhoA/ROCK pathway mediates p38 ...... microglia in neuropathic pain.
@nl
prefLabel
RhoA/ROCK pathway mediates p38 ...... microglia in neuropathic pain.
@en
RhoA/ROCK pathway mediates p38 ...... microglia in neuropathic pain.
@nl
P2093
P2860
P921
P356
P1433
P1476
RhoA/ROCK pathway mediates p38 ...... microglia in neuropathic pain
@en
P2093
Emiko Tatsumi
Hiroki Yamanaka
Kimiko Kobayashi
Koichi Noguchi
Masafumi Sakagami
P2860
P304
P356
10.1002/GLIA.22745
P50
P577
2014-08-14T00:00:00Z