Acquired Resistance to the Hsp90 Inhibitor, Ganetespib, in KRAS-Mutant NSCLC Is Mediated via Reactivation of the ERK-p90RSK-mTOR Signaling Network.
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Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic ApproachTargeting chaperonin containing TCP1 (CCT) as a molecular therapeutic for small cell lung cancer.HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome.HSP90 inhibition targets autophagy and induces a CASP9-dependent resistance mechanism in NSCLC.Reactivation of the p90RSK-CDC25C Pathway Leads to Bypass of the Ganetespib-Induced G2-M Arrest and Mediates Acquired Resistance to Ganetespib in KRAS-Mutant NSCLC.Combination Kinase Inhibitor Treatment Suppresses Rift Valley Fever Virus Replication.
P2860
Acquired Resistance to the Hsp90 Inhibitor, Ganetespib, in KRAS-Mutant NSCLC Is Mediated via Reactivation of the ERK-p90RSK-mTOR Signaling Network.
description
2017 nî lūn-bûn
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2017年の論文
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name
Acquired Resistance to the Hsp ...... p90RSK-mTOR Signaling Network.
@en
Acquired Resistance to the Hsp ...... p90RSK-mTOR Signaling Network.
@nl
type
label
Acquired Resistance to the Hsp ...... p90RSK-mTOR Signaling Network.
@en
Acquired Resistance to the Hsp ...... p90RSK-mTOR Signaling Network.
@nl
prefLabel
Acquired Resistance to the Hsp ...... p90RSK-mTOR Signaling Network.
@en
Acquired Resistance to the Hsp ...... p90RSK-mTOR Signaling Network.
@nl
P2093
P2860
P1476
Acquired Resistance to the Hsp ...... -p90RSK-mTOR Signaling Network
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P2093
Eric H-B Huang
Ian Christie
Suman Chatterjee
Timothy F Burns
P2860
P304
P356
10.1158/1535-7163.MCT-16-0677
P50
P577
2017-02-06T00:00:00Z