Three histamine receptors (H1, H2 and H3) visualized in the brain of human and non-human primates.
about
Distribution of histamine H3-receptor binding in the normal human basal ganglia: comparison with Huntington's and Parkinson's disease casesStable expression of human H1-histamine-receptor cDNA in Chinese hamster ovary cells. Pharmacological characterisation of the protein, tissue distribution of messenger RNA and chromosomal localisation of the geneThe histamine H3 receptor: an attractive target for the treatment of cognitive disordersHistamine and the striatumInternational Union of Basic and Clinical Pharmacology. XCVIII. Histamine ReceptorsHistamine H3 receptors and its antagonism as a novel mechanism for antipsychotic effect: a current preclinical & clinical perspectiveIdentification and characterization of ZEL-H16 as a novel agonist of the histamine H3 receptorGenetic Analysis of Histamine Signaling in Larval Zebrafish Sleep.Isolation and characterization of a novel conus peptide with apparent antinociceptive activity.Genetic variability of histamine receptors in patients with Parkinson's disease.Effects of histamine H(3) receptor activation on the behavioral-stimulant effects of methamphetamine and cocaine in mice and squirrel monkeys.Novel chalcone-based fluorescent human histamine h(3) receptor ligands as pharmacological tools.Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice.LC-MS/MS method for the determination of pitolisant: application to rat pharmacokinetic and brain penetration studies.Alzheimer's disease and age-related memory decline (preclinical)Atypical antipsychotics and the neural regulation of food intake and peripheral metabolism.Bodilisant-a novel fluorescent, highly affine histamine h3 receptor ligandRadiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofuran chemotype.Animal models of eating disordersBlockade of the brain histamine H3 receptor by JNJ-39220675: preclinical PET studies with [¹¹C]GSK189254 in anesthetized baboon.Safety, tolerability and pharmacokinetics of the histamine H3 receptor antagonist, ABT-288, in healthy young adults and elderly volunteers.Histamine H3 receptor ligands break ground in a remarkable plethora of therapeutic areas.Autoregulation of enterochromaffin-like cell histamine secretion via the histamine 3 receptor subtypeCharacterization of histamine H3 receptors in Alzheimer's Disease brain and amyloid over-expressing TASTPM miceEndocannabinoid-mediated control of synaptic transmission.Ligand autoradiographical quantification of histamine H3 receptor in human dementia with Lewy bodies.Unexpectedly high affinity of a novel histamine H(3) receptor antagonist, GSK239512, in vivo in human brain, determined using PET.Several down, a few to go: histamine H3 receptor ligands making the final push towards the market?Histamine in brain development.The histaminergic network in the brain: basic organization and role in disease.Recent evidence and potential mechanisms underlying weight gain and insulin resistance due to atypical antipsychotics.(11) C-labeled and (18) F-labeled PET ligands for subtype-specific imaging of histamine receptors in the brain.Histamine in migraine and brain.Qsar Modeling Of Histamine H3r Antagonists/Inverse Agonists As Future Drugs For Neurodegenerative Diseases.The Histamine H3 Receptor: Structure, Pharmacology, and Function.The role of cortical and hypothalamic histamine-3 receptors in the modulation of central histamine neurotransmission: an in vivo electrophysiology and microdialysis study.Pharmacokinetics, pharmacodynamics and safety of CEP-26401, a high-affinity histamine-3 receptor antagonist, following single and multiple dosing in healthy subjects.Agonist-induced activation of histamine H3 receptor signals to extracellular signal-regulated kinases 1 and 2 through PKC-, PLD-, and EGFR-dependent mechanisms.Recent advances in the development of histamine H3 antagonists.Endothelium-dependent relaxation of rat aorta to a histamine H(3) agonist is reduced by inhibitors of nitric oxide synthase, guanylate cyclase and Na,K-ATPase.
P2860
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P2860
Three histamine receptors (H1, H2 and H3) visualized in the brain of human and non-human primates.
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年学术文章
@wuu
1990年学术文章
@zh
1990年学术文章
@zh-cn
1990年学术文章
@zh-hans
1990年学术文章
@zh-my
1990年学术文章
@zh-sg
1990年學術文章
@yue
1990年學術文章
@zh-hant
name
Three histamine receptors (H1, ...... human and non-human primates.
@en
Three histamine receptors (H1, ...... human and non-human primates.
@nl
type
label
Three histamine receptors (H1, ...... human and non-human primates.
@en
Three histamine receptors (H1, ...... human and non-human primates.
@nl
prefLabel
Three histamine receptors (H1, ...... human and non-human primates.
@en
Three histamine receptors (H1, ...... human and non-human primates.
@nl
P2093
P1433
P1476
Three histamine receptors (H1, ...... f human and non-human primates
@en
P2093
J C Schwartz
J M Arrang
J M Palacios
M I Martinez-Mir
P304
P356
10.1016/0006-8993(90)91240-H
P407
P50
P577
1990-09-01T00:00:00Z