MED23 mutation links intellectual disability to dysregulation of immediate early gene expression.
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Mediator recruitment to heat shock genes requires dual Hsf1 activation domains and mediator tail subunits Med15 and Med16Disorders of Transcriptional Regulation: An Emerging Category of Multiple Malformation SyndromesFunctional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architectureFrom neural development to cognition: unexpected roles for chromatin.Structure, assembly and dynamics of macromolecular complexes by single particle cryo-electron microscopy.Transcriptional regulation and its misregulation in disease.The role of nuclear bodies in gene expression and disease.Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity.Mediator complex dependent regulation of cardiac development and disease.A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication.RNA polymerase II transcription elongation control.Genome-wide association of mediator and RNA polymerase II in wild-type and mediator mutant yeastThe Mediator complex of Caenorhabditis elegans: insights into the developmental and physiological roles of a conserved transcriptional coregulator.Regulation of primary response genes.Recruitment of Mediator Complex by Cell Type and Stage-Specific Factors Required for Tissue-Specific TAF Dependent Gene Activation in an Adult Stem Cell Lineage.Redefining the MED13L syndromeMediator Subunit Med28 Is Essential for Mouse Peri-Implantation Development and Pluripotency.Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation.Dosage changes of MED13L further delineate its role in congenital heart defects and intellectual disability.Mediator links transcription and DNA repair by facilitating Rad2/XPG recruitmentCYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome.Genetic variation in the epigenetic machinery and mental health.Mechanisms of Mediator complex action in transcriptional activation.The Molecular Genetics of Autosomal Recessive Nonsyndromic Intellectual Disability: a Mutational Continuum and Future Recommendations.Upregulation of mediator MED23 in non-small-cell lung cancer promotes the growth, migration, and metastasis of cancer cells.Mediator independently orchestrates multiple steps of preinitiation complex assembly in vivoVariants in Antiviral Genes are Risk Factors for Cognitive Decline and Dementia.LRP8-Reelin-Regulated Neuronal Enhancer Signature Underlying Learning and Memory Formation.Homozygous missense mutation in MED25 segregates with syndromic intellectual disability in a large consanguineous family.MED12-related XLID disorders are dose-dependent of immediate early genes (IEGs) expression.Expression and purification of a soluble ESX-binding core domain of SUR2.The mediator subunit Med23 contributes to controlling T-cell activation and prevents autoimmunity.Toward understanding of the mechanisms of Mediator function in vivo: Focus on the preinitiation complex assembly.MED20 mutation associated with infantile basal ganglia degeneration and brain atrophy.Transcription regulation by the Mediator complex.Array-CGH in children with mild intellectual disability: a population-based study.De novo mutations in genes of mediator complex causing syndromic intellectual disability: mediatorpathy or transcriptomopathy?MED23-associated refractory epilepsy successfully treated with the ketogenic diet.MED13L loss-of-function variants in two patients with syndromic Pierre Robin sequence.MED23-associated intellectual disability in a non-consanguineous family.
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P2860
MED23 mutation links intellectual disability to dysregulation of immediate early gene expression.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
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2011年學術文章
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name
MED23 mutation links intellect ...... mediate early gene expression.
@en
MED23 mutation links intellect ...... mediate early gene expression.
@nl
type
label
MED23 mutation links intellect ...... mediate early gene expression.
@en
MED23 mutation links intellect ...... mediate early gene expression.
@nl
prefLabel
MED23 mutation links intellect ...... mediate early gene expression.
@en
MED23 mutation links intellect ...... mediate early gene expression.
@nl
P2093
P2860
P356
P1433
P1476
MED23 mutation links intellect ...... mediate early gene expression.
@en
P2093
Jean-Marc Egly
Marlène Rio
Mohammed Zarhrate
Sarah Boissel
Satoru Hashimoto
P2860
P304
P356
10.1126/SCIENCE.1206638
P407
P577
2011-08-01T00:00:00Z