about
Leukocyte tyrosine kinase functions in pigment cell developmentBASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1Distinct physiological and behavioural functions for parental alleles of imprinted Grb10Developmental programming mediated by complementary roles of imprinted Grb10 in mother and pupThe potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signallingHuman growth-differentiation factor 3 (hGDF3): developmental regulation in human teratocarcinoma cell lines and expression in primary testicular germ cell tumoursAssessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge aheadFrequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor.Genomic regions regulating imprinting and insulin-like growth factor-II promoter 3 activity in transgenics: novel enhancer and silencer elements.An evolutionarily conserved intronic region controls the spatiotemporal expression of the transcription factor Sox10.Evidence that replication-associated mutation alone does not explain between-chromosome differences in substitution ratesAntagonistic roles in fetal development and adult physiology for the oppositely imprinted Grb10 and Dlk1 genes.Pathbase: a database of mutant mouse pathologyDisruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism.Coadaptation between mother and offspring: why not?Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life.Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)Dual ablation of Grb10 and Grb14 in mice reveals their combined role in regulation of insulin signaling and glucose homeostasisRNA binding by the Wilms tumor suppressor zinc finger proteins.The role of scaffold proteins in JNK signalling.Epigenetic regulation of the Igf2/H19 gene cluster.Pathbase: a new reference resource and database for laboratory mouse pathology.A luciferase-reporter vector with blue-white selection for rapid subcloning and mutational analysis of eukaryotic promoters.Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis.The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-kappaB signaling pathways.Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and show epigenetic and splicing defects in cancer.Transactivation of mouse insulin-like growth factor II (IGF-II) gene promoters by the AP-1 complex.Expression of a bacterial gene in plants mediated by infectious geminivirus DNA.Beck-Wiedemann syndrome and Wilms' tumour.Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesisIn vitro methylation of specific regions in recombinant DNA constructs by excision and religation.Structural-proliferative units and organ growth: effects of insulin-like growth factor 2 on the growth of colon and skin.Deletion of long-range sequences at Sox10 compromises developmental expression in a mouse model of Waardenburg-Shah (WS4) syndrome.Derivation of primary choroid plexus epithelial cells from the mouse.Role of the forkhead protein FoxO1 in beta cell compensation to insulin resistance.Psg22 expression in mouse trophoblast giant cells is associated with gene inversion and co-expression of antisense long non-coding RNAs.Maternally-inherited Grb10 reduces placental size and efficiency.An enhancer element at the Igf2/H19 locus drives gene expression in both imprinted and non-imprinted tissues.Nephropathy and defective spermatogenesis in mice transgenic for a single isoform of the Wilms' tumour suppressor protein, WT1-KTS, together with one disrupted Wt1 allele.Transcriptional regulation and biological significance of the insulin like growth factor II gene.
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P50
description
biochemicus
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researcher ORCID: 0000-0001-8311-5695
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name
Andrew Ward
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Andrew Ward
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Andrew Ward
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Andrew Ward
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Andrew Ward
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type
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Andrew Ward
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Andrew Ward
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Andrew Ward
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Andrew Ward
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Andrew Ward
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prefLabel
Andrew Ward
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Andrew Ward
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Andrew Ward
@es
Andrew Ward
@nl
Andrew Ward
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1964-01-01T00:00:00Z
2000-01-01T00:00:00Z
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