One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates.
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Real-Time Analysis on Drug-Antibody Ratio of Antibody-Drug Conjugates for Synthesis, Process Optimization, and Quality ControlChemoenzymatic synthesis of glycoengineered IgG antibodies and glycosite-specific antibody-drug conjugates.Synthesis of Glycosides by Glycosynthases.Generation of efficient mutants of endoglycosidase from Streptococcus pyogenes and their application in a novel one-pot transglycosylation reaction for antibody modification.Site-specific immobilization of endoglycosidases for streamlined chemoenzymatic glycan remodeling of antibodies.Development of a Novel Sulfoxide-Containing MS-Cleavable Homobifunctional Cysteine-Reactive Cross-Linker for Studying Protein-Protein Interactions.
P2860
One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates.
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2016 nî lūn-bûn
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2016年の論文
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
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name
One-pot N-glycosylation remode ...... load antibody-drug conjugates.
@en
One-pot N-glycosylation remode ...... load antibody-drug conjugates.
@nl
type
label
One-pot N-glycosylation remode ...... load antibody-drug conjugates.
@en
One-pot N-glycosylation remode ...... load antibody-drug conjugates.
@nl
prefLabel
One-pot N-glycosylation remode ...... load antibody-drug conjugates.
@en
One-pot N-glycosylation remode ...... load antibody-drug conjugates.
@nl
P2093
P2860
P356
P1476
One-pot N-glycosylation remode ...... load antibody-drug conjugates.
@en
P2093
Bingyang Sun
Bofeng Jiang
Jinhua Dong
Liyun Yang
Mei-Yu Geng
Shuai Tang
P2860
P304
P356
10.1039/C6OB01751G
P577
2016-09-13T00:00:00Z