Structural requirements for Yersinia YopJ inhibition of MAP kinase pathwaysAMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signalingStructural analysis of Xanthomonas XopD provides insights into substrate specificity of ubiquitin-like protein proteasesKinetic and structural insights into the mechanism of AMPylation by VopS Fic domainERK7 is an autoactivated member of the MAPK familyThe CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin ACleavage of focal adhesion kinase by caspases during apoptosisTarget protease specificity of the viral serpin CrmA. Analysis of five caspasesBiochemical basis for activation of virulence genes by bile salts in Vibrio parahaemolyticus.Bile salt receptor complex activates a pathogenic type III secretion systemArp2/3-independent assembly of actin by Vibrio type III effector VopL.Fido, a novel AMPylation domain common to fic, doc, and AvrB.T3SS effector VopL inhibits the host ROS response, promoting the intracellular survival of Vibrio parahaemolyticus.Marker for type VI secretion system effectors.T-cell receptor ligation by peptide/MHC induces activation of a caspase in immature thymocytes: the molecular basis of negative selection.Intracellular Vibrio parahaemolyticus escapes the vacuole and establishes a replicative niche in the cytosol of epithelial cellsThe first engagement of partners in the Euprymna scolopes-Vibrio fischeri symbiosis is a two-step process initiated by a few environmental symbiont cellsCopper-catalyzed azide-alkyne cycloaddition (click chemistry)-based detection of global pathogen-host AMPylation on self-assembled human protein microarrays.Tipping the balance by manipulating post-translational modifications.Function of the Yersinia effector YopJ.Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation.AMPylation of Rho GTPases subverts multiple host signaling processes.AMPylation: Something Old is New AgainVibrio parahaemolyticus type VI secretion system 1 is activated in marine conditions to target bacteria, and is differentially regulated from system 2.Unfolded protein response-regulated Drosophila Fic (dFic) protein reversibly AMPylates BiP chaperone during endoplasmic reticulum homeostasis.Vibrio effector protein VopQ inhibits fusion of V-ATPase-containing membranes.A MAM7 peptide-based inhibitor of Staphylococcus aureus adhesion does not interfere with in vitro host cell function.Inhibiting AMPylation: a novel screen to identify the first small molecule inhibitors of protein AMPylation.Sequence analysis of the 47-kilodalton major integral membrane immunogen of Treponema pallidum.Outer membrane adhesion factor multivalent adhesion molecule 7 initiates host cell binding during infection by gram-negative pathogens.A distinctive role for the Yersinia protein kinase: actin binding, kinase activation, and cytoskeleton disruption.Vibrio type III effector VPA1380 is related to the cysteine protease domain of large bacterial toxinsFunctional characterization of the interaction between bacterial adhesin multivalent adhesion molecule 7 (MAM7) protein and its host cell ligands.A chemical reporter for protein AMPylation.Manipulation of kinase signaling by bacterial pathogensType VI Secretion System Toxins Horizontally Shared between Marine BacteriaGenetic instability in human ovarian cancer cell lines.Vibrio parahaemolyticus cell biology and pathogenicity determinantsType III effector VopC mediates invasion for Vibrio species.Granule-mediated killing: pathways for granzyme B-initiated apoptosis.
P50
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P50
description
American biochemist
@en
biochemicus
@nl
name
Kim Orth
@ast
Kim Orth
@en
Kim Orth
@es
Kim Orth
@nl
Kim Orth
@sl
type
label
Kim Orth
@ast
Kim Orth
@en
Kim Orth
@es
Kim Orth
@nl
Kim Orth
@sl
prefLabel
Kim Orth
@ast
Kim Orth
@en
Kim Orth
@es
Kim Orth
@nl
Kim Orth
@sl
P21
P31
P496
0000-0002-0678-7620