sameAs
Structural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from Oryza sativaCurcuminoid binding to embryonal carcinoma cells: reductive metabolism, induction of apoptosis, senescence, and inhibition of cell proliferationRevisiting curcumin chemistry part I: a new strategy for the synthesis of curcuminoids.Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in miceEffect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteersCurcumin--from molecule to biological function.Demethoxycurcumin modulates prostate cancer cell proliferation via AMPK-induced down-regulation of HSP70 and EGFR.Curcumins promote monocytic gene expression related to β-amyloid and superoxide dismutase clearance.Evaluation in vitro of synthetic curcumins as agents promoting monocytic gene expression related to β-amyloid clearance.The hypomethylation agent bisdemethoxycurcumin acts on the WIF-1 promoter, inhibits the canonical Wnt pathway and induces apoptosis in human non-small-cell lung cancer.Hypomethylation effects of curcumin, demethoxycurcumin and bisdemethoxycurcumin on WIF-1 promoter in non-small cell lung cancer cell lines.Neurodegenerative Shielding by Curcumin and Its Derivatives on Brain Lesions Induced by 6-OHDA Model of Parkinson's Disease in Albino Wistar Rats.Characterization of photovoltaic performance of the dye-sensitized solar cell with a novel ruthenium complex having a bisdemethoxycurcumin as a ligand.Studies on curcumin and curcuminoids. XXXIX. Photophysical properties of bisdemethoxycurcuminGenomic and nongenomic signaling induced by 1α,25(OH)2-vitamin D3 promotes the recovery of amyloid-β phagocytosis by Alzheimer's disease macrophages.Anticoagulant activities of curcumin and its derivative.A reduced curcuminoid analog as a novel inducer of fetal hemoglobin.Barrier protective activities of curcumin and its derivative.Curcuminoids promote neurite outgrowth in PC12 cells through MAPK/ERK- and PKC-dependent pathways.Bisdemethoxycurcumin protects endothelial cells against t-BHP-induced cell damage by regulating the phosphorylation level of ERK1/2 and Akt.A comparative study of curcuminoids to measure their effect on inflammatory and apoptotic gene expression in an Aβ plus ibotenic acid-infused rat model of Alzheimer's diseaseIsolation and identification of phase 1 metabolites of curcuminoids in ratsMetabolic and pharmacokinetic studies of curcumin, demethoxycurcumin and bisdemethoxycurcumin in mice tumor after intragastric administration of nanoparticle formulations by liquid chromatography coupled with tandem mass spectrometryDiscovering Bisdemethoxycurcumin from Curcuma longa rhizome as a potent small molecule inhibitor of human pancreatic α-amylase, a target for type-2 diabetes[Bioactivity and action modes of bisdemethoxycurcumin against Tetranychus cinnabarinus Bois. (Acari:Tetranychidae)]
P921
Q27665538-756D442D-AF0F-459B-8192-05E413B38267Q34328183-FED9EE96-0D6C-4B36-8CB6-F2F609247D4CQ35844607-E9BCABFD-2C2D-4BCE-BACF-F9EB14890B2AQ36011080-D05D7682-1933-4BFE-B525-0BC12323FD19Q36629228-13D4FFD5-296C-470C-B26C-78647B20F6D7Q38008248-82B63AAB-9F31-4C03-A18A-4AE0416A66BDQ39304801-2EFF7049-9476-4B08-8150-E83E4424ECE2Q39430478-B4E006D2-6005-4004-B0E5-BBB9BC0E0AFAQ39452327-EB5563DD-8C16-49DE-98B4-86690DD78271Q39471041-F10B5439-AFD2-456E-A11E-6D45A183F500Q39560262-F05B0E44-A828-4485-98F4-2359096C2ADCQ41853483-3C5C8624-D454-4113-AFC4-F77A5B9BBD44Q41903300-0D34E2B5-0212-4A43-8B37-A67B4F2D0B49Q42252760-BC12CC53-752F-4950-AFBE-3060AAA838B3Q43545999-E9B36A78-4365-4069-9C24-4E33A23C5785Q43879909-4069CE7B-C68D-4ED8-BB7F-6D64EBF4EE65Q44238537-BBCE6B39-AE23-4F7C-98E9-66EF4CD16067Q52620414-A8E56504-FE5F-4F6A-BA00-3851D4038C79Q54545132-05ED5708-3195-4942-97EF-89DBC4107435Q54628218-333C1292-0EFA-45A4-95AD-3A93A733616EQ84273671-67856929-C83C-40CE-B700-92C8AC613035Q84510261-2116BC33-13B1-4D46-B956-46230C7BDBDDQ84799030-9750A635-0247-494B-AA11-55A83D57E491Q84975220-777F55B5-EDDC-4F88-A4AB-EF127793A649Q84976409-1B4FA111-2566-4095-BAEF-3A3CD5AB4043
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
bisdemethoxycurcumin
@en
type
label
bisdemethoxycurcumin
@en
altLabel
(1E,6E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
@en
1,7-Bis(4-hydroxyphenyl)-1,6-Heptadiene-3,5-dione
@en
Bis(4-hydroxycinnamoyl)methane
@en
Bis(p-hydroxycinnamoyl)methane
@en
Bisdemethoxycurcumin
@en
Curcumin III
@en
Didemethoxycurcumin
@en
prefLabel
bisdemethoxycurcumin
@en
P6689
P2581
P592
P6366
P661
P662
P665
P683
P1579
P2017
C1=CC(=CC=C1/C=C/C(=O)CC(=O)/C=C/C2=CC=C(C=C2)O)O
P2067
P231
33171-05-0
P233
C1=CC(=CC=C1C=CC(=O)CC(=O)C=CC2=CC=C(C=C2)O)O
P234
1S/C19H16O4/c20-16-7-1-14(2-8- ...... h1-12,20-21H,13H2/b11-5+,12-6+
P235
PREBVFJICNPEKM-YDWXAUTNSA-N
P2581
P274
P279
P3117
DTXSID00872663
P4964
splash10-000f-0900000000-b6262ce6a5bc848338cc
splash10-0a4i-0009000000-c9e4fa5e0de5b0c0d892
P592
CHEMBL105350
P6366
2775863786
2908618956
P652
2EFO1BP34R