Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.
about
Comprehensive copy number and gene expression profiling of the 17q23 amplicon in human breast cancerNo evidence for involvement of SDHD in neuroblastoma pathogenesisPositional and functional mapping of a neuroblastoma differentiation gene on chromosome 1111q deletion in neuroblastoma: a review of biological and clinical implications.CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23Widespread dysregulation of MiRNAs by MYCN amplification and chromosomal imbalances in neuroblastoma: association of miRNA expression with survival.Chromosomal and microRNA expression patterns reveal biologically distinct subgroups of 11q- neuroblastomaMechanism and relevance of ploidy in neuroblastoma.MicroRNA involvement in the pathogenesis of neuroblastoma: potential for microRNA mediated therapeutics.Clinical categories of neuroblastoma are associated with different patterns of loss of heterozygosity on chromosome arm 1p.Neuroblastoma tumour genetics: clinical and biological aspects.Chromosomal localization of DNA amplifications in neuroblastoma tumors using cDNA microarray comparative genomic hybridization.High-level amplification at 17q23 leads to coordinated overexpression of multiple adjacent genes in breast cancer.Chromosomal CGH identifies patients with a higher risk of relapse in neuroblastoma without MYCN amplification.Gain of chromosome arm 17q is associated with unfavourable prognosis in neuroblastoma, but does not involve mutations in the somatostatin receptor 2(SSTR2) gene at 17q24.Neuroblastomas with chromosome 11q loss and single copy MYCN comprise a biologically distinct group of tumours with adverse prognosis.Numerical and structural aberrations in advanced neuroblastoma tumours by CGH analysis; survival correlates with chromosome 17 status.The genetic tumor background is an important determinant for heterogeneous MYCN-amplified neuroblastoma.The connections between neural crest development and neuroblastoma.Genetic stratification of neuroblastoma for treatment tailoring.New insights into the genetics of neuroblastoma.Distinct cytogenetic pathways of advanced-stage neuroblastoma tumors, detected by spectral karyotyping.Combined M-FISH and CGH analysis allows comprehensive description of genetic alterations in neuroblastoma cell lines.Mutational dynamics between primary and relapse neuroblastomas.Chromosome 3p microsatellite allelotyping in neuroblastoma: a report on the technical hurdles.Chromosome 2 short arm translocations revealed by M-FISH analysis of neuroblastoma cell lines.Region-specific detection of neuroblastoma loss of heterozygosity at multiple loci simultaneously using a SNP-based tag-array platform.The emerging molecular pathogenesis of neuroblastoma: implications for improved risk assessment and targeted therapy.MiRNA Influences in Neuroblast Modulation: An Introspective Analysis.Multicentre analysis of patterns of DNA gains and losses in 204 neuroblastoma tumors: how many genetic subgroups are there?The mutational landscape of MYCN, Lin28b and ALKF1174L driven murine neuroblastoma mimics human disease.Novel risk stratification of patients with neuroblastoma by genomic signature, which is independent of molecular signature.Allelic deletion at 11q23 is common in MYCN single copy neuroblastomasTBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets
P2860
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P2860
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.
@en
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.
@nl
type
label
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.
@en
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.
@nl
prefLabel
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.
@en
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization.
@nl
P2093
P2860
P1476
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization
@en
P2093
A De Paepe
E Schuuring
F Speleman
J Gyselinck
M Van Gele
P2860
P304
P356
10.1002/(SICI)1098-2264(199810)23:2<141::AID-GCC7>3.0.CO;2-2
P577
1998-10-01T00:00:00Z