Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice.

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Modeling Parkinson's Disease in Drosophila: What Have We Learned for Dominant Traits?

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Q54114687-DEBDDD68-4902-4591-A07B-0795B9DDDDE7

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Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年學術文章

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Robust kinase- and age-depende ...... LRRK2 G2019S transgenic mice.

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Robust kinase- and age-depende ...... LRRK2 G2019S transgenic mice.

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type

Item

label

Robust kinase- and age-depende ...... LRRK2 G2019S transgenic mice.

@en

Robust kinase- and age-depende ...... LRRK2 G2019S transgenic mice.

@nl

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Robust kinase- and age-depende ...... LRRK2 G2019S transgenic mice.

@en

Robust kinase- and age-depende ...... LRRK2 G2019S transgenic mice.

@nl

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Robust kinase- and age-depende ...... LRRK2 G2019S transgenic mice.

@en

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Byoung Dae Lee

http://www.w3.org/2001/XMLSchema#string

Deborah A Swing

http://www.w3.org/2001/XMLSchema#string

Haisong Jiang

http://www.w3.org/2001/XMLSchema#string

Han Seok Ko

http://www.w3.org/2001/XMLSchema#string

Jeannette N Stankowski

http://www.w3.org/2001/XMLSchema#string

Jonathan C Grima

http://www.w3.org/2001/XMLSchema#string

Lino Tessarollo

http://www.w3.org/2001/XMLSchema#string

Lorraine Iacovitti

http://www.w3.org/2001/XMLSchema#string

Qinfang Liu

http://www.w3.org/2001/XMLSchema#string

Senthilkumar S Karuppagounder

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P2860

Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.

Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice

LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis

LRRK2 functions in synaptic vesicle endocytosis through a kinase-dependent mechanism

Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice

No dopamine cell loss or changes in cytoskeleton function in transgenic mice expressing physiological levels of wild type or G2019S mutant LRRK2 and in human fibroblasts

Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S

Regulation of LRRK2 expression points to a functional role in human monocyte maturation

Defining the epithelial stem cell niche in skin

Parkinson's disease

P31

scholarly article

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10.1073/PNAS.1712648115

http://www.w3.org/2001/XMLSchema#string

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English

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Ted M. Dawson

P577

2018-01-31T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29386392

http://www.w3.org/2001/XMLSchema#string

P921

dopamine

norepinephrine

P932

5816154

http://www.w3.org/2001/XMLSchema#string

Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice.

about

P2860

P2860

Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice.

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P1433

P1476

P2093

P2860

P31

P356

P407

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P31

P356

P407

P50

P577

P698

P921

P932