Consequences of SPAK inactivation on Hyperkalemic Hypertension caused by WNK1 mutations: evidence for differential roles of WNK1 and WNK4.

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Consequences of SPAK inactivation on Hyperkalemic Hypertension caused by WNK1 mutations: evidence for differential roles of WNK1 and WNK4.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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Consequences of SPAK inactivat ...... ential roles of WNK1 and WNK4.

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Consequences of SPAK inactivat ...... ential roles of WNK1 and WNK4.

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Consequences of SPAK inactivat ...... ential roles of WNK1 and WNK4.

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Consequences of SPAK inactivat ...... ential roles of WNK1 and WNK4.

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Consequences of SPAK inactivat ...... ential roles of WNK1 and WNK4.

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Consequences of SPAK inactivat ...... ential roles of WNK1 and WNK4.

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P1476

Consequences of SPAK inactivat ...... ential roles of WNK1 and WNK4.

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P2093

Chloé Rafael

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Christelle Soukaseum

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Juliette Hadchouel

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Perrine Frère

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Véronique Baudrie

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P2860

KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron

Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter

Human hypertension caused by mutations in WNK kinases

The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases

Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention

Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)

A novel Ste20-related proline/alanine-rich kinase (SPAK)-independent pathway involving calcium-binding protein 39 (Cab39) and serine threonine kinase with no lysine member 4 (WNK4) in the activation of Na-K-Cl cotransporters.

Regulation of with-no-lysine kinase signaling by Kelch-like proteins.

A new methodology for quantification of alternatively spliced exons reveals a highly tissue-specific expression pattern of WNK1 isoforms.

SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction.

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3249

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scholarly article

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10.1038/S41598-018-21405-X

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English

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2018-02-19T00:00:00Z

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29459793

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5818654

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