Maternal embryonic leucine zipper kinase is a novel target for proliferation-associated high-risk myeloma.

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Challenges in validating candidate therapeutic targets in cancer.Maternal embryonic leucine zipper kinase inhibitor OTSSP167 has preclinical activity on multiple myeloma bone disease.

P2860

Q50123858-6287C465-C8CA-4CE6-A6D2-0CE2C03AF276 Q54110801-403BE974-53E7-44F5-8BF8-1782B70A3982

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Maternal embryonic leucine zipper kinase is a novel target for proliferation-associated high-risk myeloma.

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http://www.wikidata.org/entity/Q49869942

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh-hant

name

Maternal embryonic leucine zip ...... -associated high-risk myeloma.

@en

Maternal embryonic leucine zip ...... -associated high-risk myeloma.

@nl

type

Item

label

Maternal embryonic leucine zip ...... -associated high-risk myeloma.

@en

Maternal embryonic leucine zip ...... -associated high-risk myeloma.

@nl

prefLabel

Maternal embryonic leucine zip ...... -associated high-risk myeloma.

@en

Maternal embryonic leucine zip ...... -associated high-risk myeloma.

@nl

P1476

Maternal embryonic leucine zip ...... -associated high-risk myeloma.

@en

P2093

Arnold Bolomsky

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Jo Caers

http://www.w3.org/2001/XMLSchema#string

Joséphine Muller

http://www.w3.org/2001/XMLSchema#string

Karin Schlangen

http://www.w3.org/2001/XMLSchema#string

Kathrin Stangelberger

http://www.w3.org/2001/XMLSchema#string

Niklas Zojer

http://www.w3.org/2001/XMLSchema#string

Roy Heusschen

http://www.w3.org/2001/XMLSchema#string

Wolfgang Schreiner

http://www.w3.org/2001/XMLSchema#string

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OTSSP167 Abrogates Mitotic Checkpoint through Inhibiting Multiple Mitotic Kinases

Microenvironmental influence on pre-clinical activity of polo-like kinase inhibition in multiple myeloma: implications for clinical translation

Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells

Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation

SUMOylation inhibits FOXM1 activity and delays mitotic transition.

Maternal embryonic leucine zipper kinase: key kinase for stem cell phenotype in glioma and other cancers.

MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.

Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway

Expression, adverse prognostic significance and therapeutic small molecule inhibition of Polo-like kinase 1 in multiple myeloma.

Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma.

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325-335

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scholarly article

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10.3324/HAEMATOL.2017.172973

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P433

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103

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Heinz Ludwig

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2017-11-09T00:00:00Z

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29122991

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P932

5792277

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Maternal embryonic leucine zipper kinase is a novel target for proliferation-associated high-risk myeloma.

about

P2860

P2860

Maternal embryonic leucine zipper kinase is a novel target for proliferation-associated high-risk myeloma.

description

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type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932