Phase II study of oral JAK1/JAK2 inhibitor ruxolitinib in advanced relapsed/refractory Hodgkin lymphoma.

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Ruxolitinib significantly enhances in vitro apoptosis in Hodgkin lymphoma and primary mediastinal B-cell lymphoma and survival in a lymphoma xenograft murine model.

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P2860

Phase II study of oral JAK1/JAK2 inhibitor ruxolitinib in advanced relapsed/refractory Hodgkin lymphoma.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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name

Phase II study of oral JAK1/JA ...... d/refractory Hodgkin lymphoma.

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Phase II study of oral JAK1/JA ...... d/refractory Hodgkin lymphoma.

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type

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Phase II study of oral JAK1/JA ...... d/refractory Hodgkin lymphoma.

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Phase II study of oral JAK1/JA ...... d/refractory Hodgkin lymphoma.

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Phase II study of oral JAK1/JA ...... d/refractory Hodgkin lymphoma.

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Phase II study of oral JAK1/JA ...... d/refractory Hodgkin lymphoma.

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P1476

A phase II study of the oral J ...... ed/refractory Hodgkin lymphoma

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P2093

Amine Belhabri

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Aspasia Stamatoullas

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Eric Van Den Neste

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Franck Morschhauser

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Gregor Verhoef

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Hervé Ghesquieres

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Hélène A Poirel

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Ioanna-Andrea Stoian

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Laurent Knoops

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Marc André

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P2860

How ruxolitinib modified the outcome in myelofibrosis: focus on overall survival, allele burden reduction and fibrosis changes.

Three-year efficacy, safety, and survival findings from COMFORT-II, a phase 3 study comparing ruxolitinib with best available therapy for myelofibrosis.

Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma.

Molecular karyotypes of Hodgkin and Reed-Sternberg cells at disease onset reveal distinct copy number alterations in chemosensitive versus refractory Hodgkin lymphoma

Lestaurtinib inhibition of the Jak/STAT signaling pathway in hodgkin lymphoma inhibits proliferation and induces apoptosis

Refinement of 1p36 alterations not involving PRDM16 in myeloid and lymphoid malignancies

Brentuximab vedotin (SGN-35) for relapsed CD30-positive lymphomas.

Phase I study of a novel oral Janus kinase 2 inhibitor, SB1518, in patients with relapsed lymphoma: evidence of clinical and biologic activity in multiple lymphoma subtypes.

The JAK inhibitor AZD1480 regulates proliferation and immunity in Hodgkin lymphoma.

Selective targeting of JAK/STAT signaling is potentiated by Bcl-xL blockade in IL-2-dependent adult T-cell leukemia

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840-848

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scholarly article

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10.3324/HAEMATOL.2017.180554

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103

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René-Olivier Casasnovas

Corinne Haioun

Anne-Ségolène Cottereau

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2018-01-19T00:00:00Z

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29351986

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P932

5927969

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Phase II study of oral JAK1/JAK2 inhibitor ruxolitinib in advanced relapsed/refractory Hodgkin lymphoma.

about

P2860

P2860

Phase II study of oral JAK1/JAK2 inhibitor ruxolitinib in advanced relapsed/refractory Hodgkin lymphoma.

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P1476

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P698

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P433

P478

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