Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD.

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Macrophage Uptake of Necrotic Cell DNA Activates the AIM2 Inflammasome to Regulate a Proinflammatory Phenotype in CKD.

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2018 nî lūn-bûn

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2018年の論文

@ja

2018年学术文章

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2018年学术文章

@zh

2018年学术文章

@zh-cn

2018年学术文章

@zh-hans

2018年学术文章

@zh-my

2018年学术文章

@zh-sg

2018年學術文章

@yue

2018年學術文章

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name

Macrophage Uptake of Necrotic ...... inflammatory Phenotype in CKD.

@en

Macrophage Uptake of Necrotic ...... inflammatory Phenotype in CKD.

@nl

type

Item

label

Macrophage Uptake of Necrotic ...... inflammatory Phenotype in CKD.

@en

Macrophage Uptake of Necrotic ...... inflammatory Phenotype in CKD.

@nl

prefLabel

Macrophage Uptake of Necrotic ...... inflammatory Phenotype in CKD.

@en

Macrophage Uptake of Necrotic ...... inflammatory Phenotype in CKD.

@nl

P1476

Macrophage Uptake of Necrotic ...... oinflammatory Phenotype in CKD

@en

P2093

Arthur Lau

http://www.w3.org/2001/XMLSchema#string

Craig N Jenne

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Daniel A Muruve

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Hallgrimur Benediktsson

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Henry J Duff

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Hyunjae Chung

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Jaye M Platnich

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Paul L Beck

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P2860

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

Tubulointerstitial injury and the progression of chronic kidney disease

Gout-associated uric acid crystals activate the NALP3 inflammasome

Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation

Non-canonical inflammasome activation targets caspase-11

HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF

P304

1165-1181

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P31

scholarly article

P356

10.1681/ASN.2017080863

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Takanori Komada

P577

2018-02-09T00:00:00Z

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P698

29439156

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P921

inflammasome

P932

5875955

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