about
Mechanisms of action of methotrexateOutcomes related to methotrexate dose and route of administration in patients with rheumatoid arthritis: a systematic literature reviewClinical trial development for biosimilarsRequirements for T lymphocyte migration in explanted lymph nodes.Endogenous adenosine maintains cartilage homeostasis and exogenous adenosine inhibits osteoarthritis progression.Adenosine A(2A) receptors promote collagen production by a Fli1- and CTGF-mediated mechanism.A2A adenosine receptor stimulation decreases foam cell formation by enhancing ABCA1-dependent cholesterol efflux.The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.Adenosine A1 receptors (A1Rs) play a critical role in osteoclast formation and function.Caffeine, a drug for all seasons.Identification of C1q as the heat-labile serum cofactor required for immune complexes to stimulate endothelial expression of the adhesion molecules E-selectin and intercellular and vascular cell adhesion molecules 1.Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death.Regulation of foam cells by adenosine.Activation of EPAC1/2 is essential for osteoclast formation by modulating NFκB nuclear translocation and actin cytoskeleton rearrangementsInterferon-gamma impedes reverse cholesterol transport and promotes foam cell transformation in THP-1 human monocytes/macrophages.A prize for the foreign-born.Adenosine A2A receptors play an active role in mouse bone marrow-derived mesenchymal stem cell development.Designing and implementing INTREPID, an intensive program in translational research methodologies for new investigatorsRestraint stress fails to modulate cutaneous hypersensitivity responses in mice lacking the adenosine A1 receptor.Suppression of inflammation by low-dose methotrexate is mediated by adenosine A2A receptor but not A3 receptor activation in thioglycollate-induced peritonitis.Adenosine in fibrosis.Adenosine A2A receptor blockade or deletion diminishes fibrocyte accumulation in the skin in a murine model of scleroderma, bleomycin-induced fibrosis.Direct or indirect stimulation of adenosine A2A receptors enhances bone regeneration as well as bone morphogenetic protein-2.Biosimilars: the debate continues.Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosisAdenosine promotes wound healing and mediates angiogenesis in response to tissue injury via occupancy of A(2A) receptors.Brief Report: Methotrexate Prevents Wear Particle-Induced Inflammatory Osteolysis in Mice Via Activation of Adenosine A2A Receptor.Cholesterol 27-hydroxylase but not apolipoprotein apoE contributes to A2A adenosine receptor stimulated reverse cholesterol transportAdenosine A(2A) receptor ligation inhibits osteoclast formation.Adenosine A1 receptor regulates osteoclast formation by altering TRAF6/TAK1 signaling.Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors.Adenosine in inflammatory joint diseases.Wound healing is impaired in MyD88-deficient mice: a role for MyD88 in the regulation of wound healing by adenosine A2A receptors.Pharmacological blockade of adenosine A2A receptors diminishes scarringAdenosine: a physiological modulator of superoxide anion generation by human neutrophils.Purinergic signaling in scarring.Adenosine A2A receptor plays an important role in radiation-induced dermal injuryAdenosine receptor activation ameliorates type 1 diabetes.A public-private partnership: the New York University-Health and Hospitals Corporation Clinical and Translational Science Institute.Teaching Translational Research to Medical Students: The New York University School of Medicine's Master's of Science in Clinical Investigation Dual-Degree Program.
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description
hulumtues
@sq
researcher
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wetenschapper
@nl
հետազոտող
@hy
name
Bruce N Cronstein
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Bruce N Cronstein
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Bruce N Cronstein
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Bruce N Cronstein
@nl
Bruce N Cronstein
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type
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Bruce N Cronstein
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Bruce N Cronstein
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Bruce N Cronstein
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Bruce N Cronstein
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Bruce N Cronstein
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prefLabel
Bruce N Cronstein
@ast
Bruce N Cronstein
@en
Bruce N Cronstein
@es
Bruce N Cronstein
@nl
Bruce N Cronstein
@sl
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P21
P31
P496
0000-0002-4295-7383