Epigenetic targeting of Notch1-driven transcription using the HDACi panobinostat is a potential therapy against T-cell acute lymphoblastic leukemia.

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Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML.

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Epigenetic targeting of Notch1-driven transcription using the HDACi panobinostat is a potential therapy against T-cell acute lymphoblastic leukemia.

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http://www.wikidata.org/entity/Q50073190

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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name

Epigenetic targeting of Notch1 ...... acute lymphoblastic leukemia.

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Epigenetic targeting of Notch1 ...... acute lymphoblastic leukemia.

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Epigenetic targeting of Notch1 ...... acute lymphoblastic leukemia.

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Epigenetic targeting of Notch1 ...... acute lymphoblastic leukemia.

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Epigenetic targeting of Notch1 ...... acute lymphoblastic leukemia.

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Epigenetic targeting of Notch1 ...... acute lymphoblastic leukemia.

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P1476

Epigenetic targeting of Notch1 ...... acute lymphoblastic leukemia.

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P2093

B P Martin

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I Y Kong

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K M Ramsbottom

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M Waibel

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S J Vervoort

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P2860

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

Anticancer activities of histone deacetylase inhibitors

T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments.

PANORAMA 2: panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomib-refractory myeloma.

Panobinostat in combination with bortezomib in patients with relapsed or refractory peripheral T-cell lymphoma: an open-label, multicentre phase 2 trial.

Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia

Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors.

Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.

Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma

c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.

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leu.2017.282

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237-241

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scholarly article

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10.1038/LEU.2017.282

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Ricky W Johnstone

Susanne Heinzel

Edwin D Hawkins

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2017-09-15T00:00:00Z

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1091787693

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28914259

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leukemia

Epigenetic targeting of Notch1-driven transcription using the HDACi panobinostat is a potential therapy against T-cell acute lymphoblastic leukemia.

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P2860

P2860

Epigenetic targeting of Notch1-driven transcription using the HDACi panobinostat is a potential therapy against T-cell acute lymphoblastic leukemia.

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