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Development and validation of a luminescence-based, medium-throughput assay for drug screening in Schistosoma mansoniDiscovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive SystemsA novel polyclonal antibody library for expression profiling of poorly characterized, membrane and secreted human proteins.Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACsPeptide nucleic acids targeting β-globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cellsDiscovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production.Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin.Nuclear factor (erythroid-derived 2)-like 2 (NRF2) drug discovery: Biochemical toolbox to develop NRF2 activators by reversible binding of Kelch-like ECH-associated protein 1 (KEAP1).Vitamin B12 ameliorates the phenotype of a mouse model of DiGeorge syndrome.Identification of a series of 4-[3-(quinolin-2-yl)-1,2,4-oxadiazol-5-yl]piperazinyl ureas as potent smoothened antagonist hedgehog pathway inhibitors.Quantifying autophagy using novel LC3B and p62 TR-FRET assays.Identification by High-Throughput Screening of Pseudomonas Acyl–Coenzyme A Synthetase InhibitorsIdentification and binding mode of a novel Leishmania Trypanothione reductase inhibitor from high throughput screeningIdentification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg productionFish-derived antimicrobial peptides: Activity of a chionodracine mutant against bacterial models and human bacterial pathogensProteolytic activation cascade of the Netherton syndrome-defective protein, LEKTI, in the epidermis: implications for skin homeostasisN-(2-alkylaminoethyl)-4-(1,2,4-oxadiazol-5-yl)piperazine-1-carboxamides as highly potent smoothened antagonistsAspergillus olivimuriae sp. nov., a halotolerant species isolated from olive brineDevelopment of a Broadly Applicable Assay for Measurement of Glycan-Directed Enzymatic ActivityJanus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitorsDevelopment and characterization of cellular biosensors for HTS of erythroid differentiation inducers targeting the transcriptional activity of γ-globin and β-globin gene promotersInhibiting pathologically active ADAM10 rescues synaptic and cognitive decline in Huntington's diseaseImproved Selective Class I HDAC and Novel Selective HDAC3 Inhibitors: Beyond Hydroxamic Acids and BenzamidesDiscovery of 2-(1H-imidazo-2-yl)piperazines as a new class of potent and non-cytotoxic inhibitors of Trypanosoma brucei growth in vitro
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description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
@hy
name
Alberto Bresciani
@ast
Alberto Bresciani
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Alberto Bresciani
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Alberto Bresciani
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Alberto Bresciani
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type
label
Alberto Bresciani
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Alberto Bresciani
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Alberto Bresciani
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Alberto Bresciani
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Alberto Bresciani
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prefLabel
Alberto Bresciani
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Alberto Bresciani
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Alberto Bresciani
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Alberto Bresciani
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Alberto Bresciani
@sl
P106
P21
P31
P496
0000-0003-4491-603X