NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) - Wikidata - wikimedia - TriplyDB

NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)

NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)

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Transport of Mature mRNA derived from an Intron-Containing Transcript

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Q45317542-051979D0-72FF-4C9B-8D6F-442766EE0309

P527

NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)

http://www.wikidata.org/entity/Q50295513

description

An instance of the biological ...... (minus DDX39B) in Homo sapiens

@en

biologisch proces

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NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)

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type

label

NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)

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prefLabel

NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B)

@en

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Mapping interactions between mRNA export factors in living cells

TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture

Chtop is a component of the dynamic TREX mRNA export complex

The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human

Formation of Tap/NXT1 heterodimers activates Tap-dependent nuclear mRNA export by enhancing recruitment to nuclear pore complexes

TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus

Mutually exclusive interactions drive handover of mRNA from export adaptors to TAP

The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences

The solution structure of REF2-I reveals interdomain interactions and regions involved in binding mRNA export factors and RNA.

Arginine methylation of REF/ALY promotes efficient handover of mRNA to TAP/NXF1.

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reactome:R-HSA-159101

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RNA export from nucleus

biological process

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Transport of Mature mRNA derived from an Intron-Containing Transcript

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R-HSA-159101

http://www.w3.org/2001/XMLSchema#string

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phosphate(3−) ion

polyadenylated; capped mRNA:CBC:EJC:TREX:SRSF proteins

NXF1;2:NXT1::polyadenylated; capped mRNA:CBC:EJC:TREX:SRSF proteins

P703