PIAS1;4 SUMOylates BRCA1 with SUMO1 - Wikidata - wikimedia - TriplyDB

PIAS1;4 SUMOylates BRCA1 with SUMO1

PIAS1;4 SUMOylates BRCA1 with SUMO1

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SUMOylation of DNA damage response and repair proteins

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P527

PIAS1;4 SUMOylates BRCA1 with SUMO1

http://www.wikidata.org/entity/Q50296414

description

An instance of the biological ...... CA1 with SUMO1 in Homo sapiens

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biologisch proces

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name

PIAS1;4 SUMOylates BRCA1 with SUMO1

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type

label

PIAS1;4 SUMOylates BRCA1 with SUMO1

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prefLabel

PIAS1;4 SUMOylates BRCA1 with SUMO1

@en

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Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

A novel mechanism whereby BRCA1/1a/1b fine tunes the dynamic complex interplay between SUMO-dependent/independent activities of Ubc9 on E2-induced ERalpha activation/repression and degradation in breast cancer cells

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress.

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reactome:R-HSA-2997709

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biological process

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SUMOylation of DNA damage response and repair proteins

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R-HSA-2997709

http://www.w3.org/2001/XMLSchema#string

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BRCA1 DNA repair associated

Ubiquitin conjugating enzyme E2 I

SUMO1:C93-UBE2I

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