The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation.
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L-DOPA is an endogenous ligand for OA1Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and beta-arrestinsCarboxy-terminus of CXCR7 regulates receptor localization and functionMdm2 directs the ubiquitination of beta-arrestin-sequestered cAMP phosphodiesterase-4D5Ligand-induced tyrosine phosphorylation of cysteinyl leukotriene receptor 1 triggers internalization and signaling in intestinal epithelial cellsClathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization.Beta-arrestin-dependent mu-opioid receptor-activated extracellular signal-regulated kinases (ERKs) Translocate to Nucleus in Contrast to G protein-dependent ERK activationBeta-arrestins and heterotrimeric G-proteins: collaborators and competitors in signal transductionThe structural basis of arrestin-mediated regulation of G-protein-coupled receptorsRegulation of CaMKII signaling in cardiovascular diseaseMultifaceted role of β-arrestins in inflammation and diseaseRaf-interactome in tuning the complexity and diversity of Raf function.Voltage-gated ion channel Kv4.3 is associated with Rap guanine nucleotide exchange factors and regulates angiotensin receptor type 1 signaling to small G-protein RapGPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein SignalingDopamine promotes striatal neuronal apoptotic death via ERK signaling cascadesSite-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling.beta-Arrestin 1 participates in platelet-activating factor receptor-mediated endocytosis of Streptococcus pneumoniae.Fluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting on the membrane mobility of neuropeptide Y receptorsPACAP-induced ERK activation in HEK cells expressing PAC1 receptors involves both receptor internalization and PKC signaling.Ligand-directed signalling at beta-adrenoceptorsβ-Arrestin1 mediates the endocytosis and functions of macrophage migration inhibitory factorDifferent G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor.G protein-coupled receptor sorting to endosomes and lysosomes.Beyond desensitization: physiological relevance of arrestin-dependent signaling.α1A-adrenergic receptor induces activation of extracellular signal-regulated kinase 1/2 through endocytic pathwayTeaching old receptors new tricks: biasing seven-transmembrane receptors.GnRH signaling, the gonadotrope and endocrine control of fertility.Biased signaling favoring gi over β-arrestin promoted by an apelin fragment lacking the C-terminal phenylalanineA high-content, live-cell, and real-time approach to the quantitation of ligand-induced β-Arrestin2 and Class A/Class B GPCR mobilization.Functional selectivity in adrenergic and angiotensin signaling systems.Apical and basolateral pools of proteinase-activated receptor-2 direct distinct signaling events in the intestinal epithelium.Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins.βArrestin-1 and Mcl-1 modulate self-renewal growth of cancer stem-like side-population cells in non-small cell lung cancer.Β-arrestin: a signaling molecule and potential therapeutic target for heart failure.Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathwaysBeta-agonists and asthma: too much of a good thing?Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling.β-arrestin regulates estradiol membrane-initiated signaling in hypothalamic neurons.Visualizing microtubule-dependent vasopressin type 2 receptor trafficking using a new high-affinity fluorescent vasopressin ligand.
P2860
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P2860
The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
The stability of the G protein ...... consequence of ERK activation.
@en
The stability of the G protein ...... consequence of ERK activation.
@nl
type
label
The stability of the G protein ...... consequence of ERK activation.
@en
The stability of the G protein ...... consequence of ERK activation.
@nl
prefLabel
The stability of the G protein ...... consequence of ERK activation.
@en
The stability of the G protein ...... consequence of ERK activation.
@nl
P2093
P2860
P356
P1476
The stability of the G protein ...... consequence of ERK activation.
@en
P2093
Akira Tohgo
Diane Gesty-Palmer
Eric W Choy
Kristen L Pierce
Louis M Luttrell
Marc G Caron
Robert H Oakley
Robert J Lefkowitz
Stephane Laporte
P2860
P304
P356
10.1074/JBC.M212231200
P407
P577
2002-12-06T00:00:00Z